ChemicalBook
English   Japanese   Germany   Korea

1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt

1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt, 157124-84-0, 结构式
1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
CAS号:
157124-84-0
英文名:
1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
英文别名:
BPH-652;BPH 652,BPH652;FIOQVVKPUBNHEM-UHFFFAOYSA-N;1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
中文名:
1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
中文别名:
化合物 T10587
CBNumber:
CB62609504
分子式:
C16H16K3O7PS
分子量:
500.627701
MOL File:
157124-84-0.mol

1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt化学性质

储存条件:
4°C, away from moisture
形态:
Solid
颜色:
White to off-white
水溶解性:
Water : 25 mg/mL (49.94 mM; Need ultrasonic)
安全信息

1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt性质、用途与生产工艺

生物活性

BPH-652 是 CrtM 的抑制剂,Ki 值为 1.5 nM,IC50 值为100-300 nM (S. aureus 色素形成)。

靶点

Ki: 1.5 nM (CrtM).
IC50: 100-300 nM ( S. aureus pigment formation).

体内研究

BPH-652 treatment (0.5 mg twice per day (days −1, 0, 1, and 2), Intraperitoneal injection) significantly lowers S. aureus bacterial counts in the kidneys of the mice than those of the control group (P < 0.001), with 8 of 13 below the detection threshold, versus only 2 of 14 in the control group; on average, this result corresponds to a 98% decrease in surviving bacteria in the treatment group.

Animal Model: A systemic S. aureus infection model in mice.
Dosage: 0.5 mg twice per day (days −1, 0, 1, and 2).
Administration: Intraperitoneal injection.
Result: S. aureus bacterial counts in the kidneys of the mice treated with BPH-652 were significantly lower than those of the control group.

1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt 上下游产品信息

上游原料

下游产品

1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt 试剂级价格

更新日期产品编号产品名称CAS编号包装价格
2024/04/30HY-16115BPH-6521 mg3400元
2024/04/30HY-161151-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
BPH-652
157124-84-05mg8500元

1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt 生产厂家

供应商联系电话电子邮件国家产品数优势度
斯派螺(武汉)药物研发有限公司 eric_feng1954@126.com 中国 9254 55
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 marketing@targetmol.com 美国 19892 58
天津普西唐生物医药科技有限公司 010-60605840 psaitong@jm-bio.com 中国 29778 58
TargetMol中国(陶术生物) 4008200310 marketing@tsbiochem.com 中国 24017 58
苏州美石生物科技有限公司 1173954148q meishipharma@126.com 中国 20035 58
 

157124-84-0, 1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt 相关搜索:

  • 化合物 T10587
  • 157124-84-0
  • BPH 652,BPH652
  • FIOQVVKPUBNHEM-UHFFFAOYSA-N
  • BPH-652
  • 1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
Copyright 2016 © ChemicalBook. All rights reserved