网站主页 >> CAS数据库列表 >> 1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
|
|
|
- CAS号:
- 157124-84-0
- 英文名:
- 1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
- 英文别名:
- BPH-652;BPH 652,BPH652;FIOQVVKPUBNHEM-UHFFFAOYSA-N;1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
- 中文名:
- 1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
- 中文别名:
- 化合物 T10587
- CBNumber:
- CB62609504
- 分子式:
- C16H16K3O7PS
- 分子量:
- 500.627701
- MOL File:
- 157124-84-0.mol
|
|
|
1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt化学性质
-
储存条件:
-
4°C, away from moisture
-
|
-
形态:
-
Solid
-
|
-
颜色:
-
White to off-white
-
|
-
水溶解性:
-
Water : 25 mg/mL (49.94 mM; Need ultrasonic)
-
|
1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt性质、用途与生产工艺
BPH-652 是 CrtM 的抑制剂，Ki 值为 1.5 nM，IC50 值为100-300 nM (S. aureus 色素形成)。
Ki: 1.5 nM (CrtM).
IC50: 100-300 nM (
S. aureus
pigment formation).
BPH-652 treatment (0.5 mg twice per day (days −1, 0, 1, and 2), Intraperitoneal injection) significantly lowers
S. aureus
bacterial counts in the kidneys of the mice than those of the control group (P < 0.001), with 8 of 13 below the detection threshold, versus only 2 of 14 in the control group; on average, this result corresponds to a 98% decrease in surviving bacteria in the treatment group.
|
Animal Model:
|
A systemic
S. aureus
infection model in mice.
|
|
Dosage:
|
0.5 mg twice per day (days −1, 0, 1, and 2).
|
|
Administration:
|
Intraperitoneal injection.
|
|
Result:
|
S. aureus
bacterial counts in the kidneys of the mice treated with BPH-652 were significantly lower than those of the control group.
|
1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-16115 | BPH-652 | | 1 mg | 3400元 |
| 2024/04/30 | HY-16115 | 1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
BPH-652 | 157124-84-0 | 5mg | 8500元 |
1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
生产厂家
157124-84-0, 1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt 相关搜索:
- 化合物 T10587
- 157124-84-0
- BPH 652,BPH652
- FIOQVVKPUBNHEM-UHFFFAOYSA-N
- BPH-652
- 1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt