(R)-N-BOC-3-羟基金刚烷基甘氨酸
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- CAS号:
- 1334321-39-9
- 英文名:
- (R)-N-Boc-3-hydroxyadaMantylglycine
- 英文别名:
- Boc-3-hydroxy-1-adamantyl-L-glycine;Boc-3-hydroxy-1-adamantyl-glycine;(R)-N-Boc-3-hydroxyadaMantylglycine;(R)-N-Boc-2-(3-hydroxyadamant-1-yl)glycine;Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, (αR)-;Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-diMethylethoxy)carbonyl]aMino]-3-hydroxy-, (αR)-;"(a-R)-a--[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-Tricyclo[3.3.1.13,7]decane-1-acetic acid";(alphaR)-alpha-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-hydroxytricyclo[3.3.1.1(3,7)]decane-1-acetic acid
- 中文名:
- (R)-N-BOC-3-羟基金刚烷基甘氨酸
- 中文别名:
- BOC-3-羟基-1-金刚烷基-甘氨酸;(R)-N-BOC-3-羟基金刚烷基甘氨酸;BOC-3-HYDROXY-1-ADAMANTYL-GLYCINE;(2R)-2-((叔丁氧羰基)氨基)-2-(3-羟基金刚烷-1-基)乙酸;(ALPHAR)-ALPHA-[叔丁氧羰基氨基]-3-羟基金刚烷-1-乙酸
- CBNumber:
- CB62663737
- 分子式:
- C17H27NO5
- 分子量:
- 325.4
- MOL File:
- 1334321-39-9.mol
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(R)-N-BOC-3-羟基金刚烷基甘氨酸化学性质
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熔点:
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>280°C (dec.)
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沸点:
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497.3±20.0 °C(Predicted)
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密度:
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1.296±0.06 g/cm3(Predicted)
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储存条件:
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-20°C Freezer
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溶解度:
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Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
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酸度系数(pKa):
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3.93±0.10(Predicted)
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形态:
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Solid
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颜色:
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White to Off-White
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(R)-N-BOC-3-羟基金刚烷基甘氨酸性质、用途与生产工艺
Boc-3-羟基-1-金刚烷基甘氨酸是萨克列汀的杂质，萨克列汀是二肽基肽酶-4的有效和选择性可逆抑制剂，二肽基肽酶-4用于治疗2型糖尿病。口服后迅速吸收，并具有与每日一次给药相兼容的药代动力学特征。
(R)-N-BOC-3-羟基金刚烷基甘氨酸
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1334321-39-9, (R)-N-BOC-3-羟基金刚烷基甘氨酸 相关搜索:
3-羟基金刚烷 沙格列汀杂质34 羟基沙格列汀 (1R,3R,5R)-2-[(2S)-2-氨基-2-(3-羟基-1-金刚烷基)-1-羰基乙基]-2-氮杂双环[3.1.0]己烷-3-腈(沙格列汀中间体对应杂质) 沙格列汀(R,S,R,R)异构体 N-叔丁氧羰基-L-金刚烷基甘氨酸 沙格列汀杂质16 沙格列汀(S,R,S,S)异构体 沙格列汀杂质7 沙格列汀杂质 沙格列汀(S,S,S,R)异构体 (1R,3R,5R)-2-氮杂双环[3.1.0]己烷-3-甲酰胺2,2,2-三氟乙酸盐 (S)-N-BOC-2,3-二氢吡咯-2-甲酰胺 NULL 沙格列汀杂质亚胺 沙格列汀 (1R,3R,5R)-2-[(2R)-2-氨基-2-(3-羟基-1-金刚烷基)-1-羰基乙基]-2-氮杂双环[3.1.0]己烷-3-腈(沙格列汀中间体对应杂质) 沙格列汀杂质15
- 杂质对照品
- 医药中间体
- BOC-3-羟基-1-金刚烷基-甘氨酸
- (2R)-2-((叔丁氧羰基)氨基)-2-(3-羟基金刚烷-1-基)乙酸
- BOC-3-HYDROXY-1-ADAMANTYL-GLYCINE
- (ALPHAR)-ALPHA-[叔丁氧羰基氨基]-3-羟基金刚烷-1-乙酸
- (R)-N-BOC-3-羟基金刚烷基甘氨酸
- 1334321-39-9
- Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, (αR)-
- Boc-3-hydroxy-1-adamantyl-L-glycine
- "(a-R)-a--[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-Tricyclo[3.3.1.13,7]decane-1-acetic acid"
- Boc-3-hydroxy-1-adamantyl-glycine
- (R)-N-Boc-2-(3-hydroxyadamant-1-yl)glycine
- (R)-N-Boc-3-hydroxyadaMantylglycine
- (alphaR)-alpha-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-hydroxytricyclo[3.3.1.1(3,7)]decane-1-acetic acid
- Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-diMethylethoxy)carbonyl]aMino]-3-hydroxy-, (αR)-