CMPD1
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- CAS号:
- 41179-33-3
- 英文名:
- 2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE
- 英文别名:
- CMPD-1;CMD1;SRA1;MK2a Inhibitor;CMPD-1
(CMPD 1;Steroid receptor RNA activator 1;ANTI-SOX9 antibody produced in mouse;MK2a Inhibitor - CAS 41179-33-3 - Calbiochem;ANTI-SRA1 (C-TERM) antibody produced in rabbit;Monoclonal Anti-SOX9 antibody produced in mouse
- 中文名:
- CMPD1
- 中文别名:
- 化合物CMPD1;CMPD-1,P38Α介导的MK2A磷酸化的抑制剂;4-(2'-氟-[1,1'-联苯]-4-基)-N-(4-羟基苯基)丁酰胺;4-(2'-氟-[1,1'-联苯]-4-基)-N-(4-羟基苯基)丁酰胺
- CBNumber:
- CB6840374
- 分子式:
- C22H20FNO2
- 分子量:
- 349.4
- MOL File:
- 41179-33-3.mol
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CMPD1化学性质
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熔点:
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128-130 °C
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沸点:
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585.0±50.0 °C(Predicted)
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密度:
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1.229±0.06 g/cm3(Predicted)
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储存条件:
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-20°C
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溶解度:
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Soluble to 100 mM in DMSO and to 100 mM in ethanol
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形态:
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Pale yellow solid
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酸度系数(pKa):
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10.11±0.26(Predicted)
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颜色:
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Off-white to light brown
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CMPD1性质、用途与生产工艺
CMPD1 是一种选择性且非 ATP 竞争性的 p38 MAPK 介导的 MK2 磷酸化抑制剂，表观 Ki (Kiapp) 值为 330 nM。
Ki
app
: 330 nM (MK2 phosphorylation)
CMPD1 does not inhibit p38 MAPK-mediated phosphorylation of other two substrates, MBP and ATF2.
CMPD1 induced mitotic arrest and apoptosis in U87 cells.
CMPD1 inhibits tubulin polymerisation in glioblastoma cells.
CMPD1
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/08/19 | HY-108643 | CMPD1 | | 1 mg | 590元 |
| 2024/08/19 | HY-108643 | CMPD1
CMPD1 | 41179-33-3 | 5mg | 1300元 |
41179-33-3, CMPD1 相关搜索:
- Protein Kinase
- 合成有机化合物配体
- CMPD-1,P38Α介导的MK2A磷酸化的抑制剂
- 4-(2'-氟-[1,1'-联苯]-4-基)-N-(4-羟基苯基)丁酰胺
- 4-(2'-氟-[1,1'-联苯]-4-基)-N-(4-羟基苯基)丁酰胺
- 化合物CMPD1
- 41179-33-3
- 4-(2'-Fluoro-[1,1'-biphenyl]-4-yl)-N-(4-hydroxyphenyl)butanamide
- 2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE
- MAPK activated protein kinase 2,MAP kinase activated protein kinase 2,CMPD 1,MAPKAPK2 (MK2),inhibit,Mitogen-activated protein kinase activated protein kinase 2,Inhibitor,CMPD-1,CMPD1,MAPKAP kinase 2
- CMPD-1
- [1,1'-Biphenyl]-4-butanamide, 2'-fluoro-N-(4-hydroxyphenyl)-
- MK2a Inhibitor - CAS 41179-33-3 - Calbiochem
- CMPD-1
(CMPD 1
- 4-(2'-fluoro-[1,1'-biphenyl]-4-yl)-N-(4-hydroxyphenyl)butanamide
- MK2a Inhibitor
- ANTI-SOX9 antibody produced in mouse
- SRA1
- Monoclonal Anti-SOX9 antibody produced in mouse
- CMD1
- Steroid receptor RNA activator 1
- ANTI-SRA1 (C-TERM) antibody produced in rabbit
- 2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE
- 4-(2'-FLUOROBIPHENYL-4-YL)-N-(4-HYDROXYPHENYL)-BUTYRAMIDE