Antagonist G TFA
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- CAS号:
- 英文名:
- Antagonist G TFA
- 英文别名:
- Antagonist G TFA
- 中文名:
- 中文别名:
- CBNumber:
- CB69041622
- 分子式:
- 分子量:
- 0
- MOL File:
- Mol file
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Antagonist G TFA性质、用途与生产工艺
Antagonist G TFA 是有效的后叶加压素 (vasopressin) 的拮抗剂。Antagonist G 也是弱的GRP 和缓激肽的弱拮抗剂。Antagonist G 可诱导 AG-1 的转录，是癌细胞对化疗增敏。
Antagonist G (0-100 μM) induces apoptosis is redox-sensitive and caspase-dependently in SCLC cells.
Antagonist G activates JNK1 in SCLC cells.
Antagonist G is not intrinsically a free radical oxygen donor but stimulates free radical generation specifically within SCLC cells (6.2-fold) and increases the activity of the redox-sensitive transcription factor AP-1 by 61%.
Cell Viability Assay
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Cell Line:
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SCLC cell lines NCI-H69, NCI-H510 and CHO-K1 cells.
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Concentration:
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0-100 μM.
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Incubation Time:
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24 h.
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Result:
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Inhibited cell growh.
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Antagonist G TFA
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