TALNETANT
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- CAS号:
- 174636-32-9
- 英文名:
- SB 223412
- 英文别名:
- CS-1123;SB 223412;Talnetant (SB 223412);SB-223412; SB223412; SB 223412;3-hydroxy-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide;(S)-N-(1-Phenylpropyl)-3-hydroxy-2-phenylquinoline-4-carboxamide;(S)-3-Hydroxy-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide;3-Hydroxy-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide;3-hydroxy-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide;(-)-3-Hydroxy-2-phenyl-N-[1(S)-phenylpropyl]quinoline-4-carboxamide
- 中文名:
- TALNETANT
- 中文别名:
- 他奈坦;他尔奈坦;化合物TALNETANT;(S)-3-羟基-2-苯基-N-(1-苯丙基)喹啉-4-甲酰胺;(S)-3-羟基-2-苯基-N-(1-苯基丙基)喹啉-4-甲酰胺;3-羟基-2-苯基-N-[(1S)-1-苯基丙基]-4-喹啉甲酰胺
- CBNumber:
- CB71333041
- 分子式:
- C25H22N2O2
- 分子量:
- 382.45
- MOL File:
- 174636-32-9.mol
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TALNETANT化学性质
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熔点:
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125.1-126.2℃
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沸点:
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580.4±50.0 °C(Predicted)
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密度:
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1.212±0.06 g/cm3(Predicted)
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储存条件:
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Sealed in dry,2-8°C
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溶解度:
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DMSO: soluble25mg/mL, clear
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形态:
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powder
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酸度系数(pKa):
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6.70±0.50(Predicted)
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颜色:
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white to beige
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旋光性 (optical activity):
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[α]/D -25 to -31°, c = 0.5 in methanol
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TALNETANT性质、用途与生产工艺
Talnetant (SB 223412)是高活性NK3受体选择性拮抗剂，Ki为1.4 nM，比对hNK-2受体的抑制性高100倍，对hNK-1无亲和性。
TALNETANT
上下游产品信息
上游原料
下游产品
174636-32-9, TALNETANT 相关搜索:
- 抑制剂
- 合成有机化合物配体
- G蛋白偶联受体&G蛋白
- 他尔奈坦
- 化合物TALNETANT
- (S)-3-羟基-2-苯基-N-(1-苯基丙基)喹啉-4-甲酰胺
- 他奈坦
- (S)-3-羟基-2-苯基-N-(1-苯丙基)喹啉-4-甲酰胺
- 3-羟基-2-苯基-N-[(1S)-1-苯基丙基]-4-喹啉甲酰胺
- 174636-32-9
- schizophrenia,SB223412,NK receptor,Inhibitor,hNK-2,Talnetant,Neurokinin Receptor,Tachykinin receptor,NK3 receptor,SB-223412,inhibit
- (S)-3-Hydroxy-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide
- 4-Quinolinecarboxamide, 3-hydroxy-2-phenyl-N-[(1S)-1-phenylpropyl]-
- Talnetant/(S)-3-hydroxy-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide
- CS-1123
- Talnetant (SB 223412)
- SB-223412; SB223412; SB 223412
- 3-Hydroxy-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide
- 3-hydroxy-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
- (S)-N-(1-Phenylpropyl)-3-hydroxy-2-phenylquinoline-4-carboxamide
- (-)-3-Hydroxy-2-phenyl-N-[1(S)-phenylpropyl]quinoline-4-carboxamide
- TALNETANT//SB223412//3-hydroxy-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxaMide
- (-)-(S)-N-(alpha-ethylbenzyl)-3-hydroxy-2-phenylquinoline-4-carboxaMide
- 3-hydroxy-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide
- SB 223412