SEN 12333
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- CAS号:
- 874450-44-9
- 英文名:
- SEN 12333
- 英文别名:
- SEN 12333;WAY 317538;SEN 12333 WAY-317538;N-[4-(3-Pyridinyl)phenyl]-4-MorpholinepentanaMide;5-Morpholino-N-(4-(pyridin-3-yl)phenyl)pentanamide;4-MorpholinepentanaMide, N-[4-(3-pyridinyl)phenyl]-;Neuroprotective,nAChR,Inhibitor,SEN-12333,WAY317538,SEN12333,Alzheimer's Disease,inhibit,WAY 317538,Nicotinic acetylcholine receptors,schizophrenia,WAY-317538
- 中文名:
- SEN 12333
- 中文别名:
- 化合物SEN 12333;5-吗啉代-N-(4-(吡啶-3-基)苯基)戊酰胺;SEN 12333,Α7烟碱乙酰胆碱受体(NACHR)激动剂
- CBNumber:
- CB72603004
- 分子式:
- C20H25N3O2
- 分子量:
- 339.43
- MOL File:
- 874450-44-9.mol
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SEN 12333化学性质
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储存条件:
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Store at RT
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溶解度:
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Soluble to 100 mM in DMSO
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形态:
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Powder
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颜色:
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White to light yellow
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SEN 12333性质、用途与生产工艺
用途
SEN 12333 is a nicotinic acetylcholine receptor (nAChR) agonist. SEN 12333 displays functional antagonism at histamine H3 receptors (IC50 = 103 nM) and weak agonist activity at human ganglionic α3 nAC
hRs (IC50 = 8.5 μM). Neuroprotective in a rodent model of quisqualic acid-induced cholinergic degeneration. SEN 12333 is a brain penetrant and orally bioavailable.
SEN 12333
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下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-107678 | SEN 12333
SEN12333 | 874450-44-9 | 5mg | 800元 |
| 2024/04/30 | HY-107678 | SEN 12333
SEN12333 | 874450-44-9 | 10mM * 1mLin DMSO | 880元 |
874450-44-9, SEN 12333 相关搜索:
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Heterocycles
- Amines
- 药靶配体
- SEN 12333,Α7烟碱乙酰胆碱受体(NACHR)激动剂
- 5-吗啉代-N-(4-(吡啶-3-基)苯基)戊酰胺
- 化合物SEN 12333
- 874450-44-9
- Neuroprotective,nAChR,Inhibitor,SEN-12333,WAY317538,SEN12333,Alzheimer's Disease,inhibit,WAY 317538,Nicotinic acetylcholine receptors,schizophrenia,WAY-317538
- 5-Morpholino-N-(4-(pyridin-3-yl)phenyl)pentanamide
- SEN 12333 WAY-317538
- WAY 317538
- N-[4-(3-Pyridinyl)phenyl]-4-MorpholinepentanaMide
- 4-MorpholinepentanaMide, N-[4-(3-pyridinyl)phenyl]-
- SEN 12333