A-770041
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- CAS号:
- 869748-10-7
- 英文名:
- A-770041
- 英文别名:
- A-770041;selective,concanavalin A,inhibit,acute rejection,Src,IL-2,Inhibitor,T cell,rat,small-molecule,A 770041,A770041,A-770041;N-[4-[1-[4-(4-acetylpiperazin-1-yl)cyclohexyl]-4-aminopyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl]-1-methylindole-2-carboxamide;N-(4-(1-(trans-4-(4-acetylpiperazin-1-yl)cyclohexyl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide;N-[4-[1-[trans-4-(4-Acetyl-1-piperazinyl)cyclohexyl]-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl]-1-methyl-1H-indole-2-carboxamide;1H-Indole-2-carboxamide, N-[4-[1-[trans-4-(4-acetyl-1-piperazinyl)cyclohexyl]-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl]-1-methyl-;N-(4-(1-((1r,4r)-4-(4-acetylpiperazin-1-yl)cyclohexyl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide
- 中文名:
- A-770041
- 中文别名:
- 化合物A-770041;N-(4-(1-(反式-4-(4-乙酰基哌嗪-1-基)环己基)-4-氨基-1H-吡唑并[3,4-D]嘧啶-3-基)-2-甲氧基苯基)-1-甲基-1H-吲哚-2-甲酰胺;N-[4-[1-[反式-4-(4-乙酰基-1-哌嗪基)环己基]-4-氨基-1H-吡唑并[3,4-D]嘧啶-3-基]-2-甲氧基苯基]-1-甲基-1H-吲哚-2-甲酰胺
- CBNumber:
- CB72627240
- 分子式:
- C34H39N9O3
- 分子量:
- 621.73
- MOL File:
- 869748-10-7.mol
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A-770041化学性质
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沸点:
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812.6±65.0 °C(Predicted)
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密度:
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1.42±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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0.1 M HCl: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 2 mg/ml
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酸度系数(pKa):
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13.21±0.70(Predicted)
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形态:
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Powder
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颜色:
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White to off-white
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A-770041性质、用途与生产工艺
A-770041是口服活性Lck抑制剂，IC50为147 nM，作用于Lck的活性较Fyn和其它Src家族激酶高300倍。
A-770041
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/11/08 | HY-11011 | A-770041
A-770041 | 869748-10-7 | 5mg | 2900元 |
| 2024/11/08 | HY-11011 | A-770041
A-770041 | 869748-10-7 | 10mM * 1mLin DMSO | 3967元 |
869748-10-7, A-770041 相关搜索:
- 抑制剂
- C34H39N9O3
- N-(4-(1-(反式-4-(4-乙酰基哌嗪-1-基)环己基)-4-氨基-1H-吡唑并[3,4-D]嘧啶-3-基)-2-甲氧基苯基)-1-甲基-1H-吲哚-2-甲酰胺
- 化合物A-770041
- N-[4-[1-[反式-4-(4-乙酰基-1-哌嗪基)环己基]-4-氨基-1H-吡唑并[3,4-D]嘧啶-3-基]-2-甲氧基苯基]-1-甲基-1H-吲哚-2-甲酰胺
- 869748-10-7
- N-(4-(1-(trans-4-(4-acetylpiperazin-1-yl)cyclohexyl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide
- selective,concanavalin A,inhibit,acute rejection,Src,IL-2,Inhibitor,T cell,rat,small-molecule,A 770041,A770041,A-770041
- 1H-Indole-2-carboxamide, N-[4-[1-[trans-4-(4-acetyl-1-piperazinyl)cyclohexyl]-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl]-1-methyl-
- N-[4-[1-[4-(4-acetylpiperazin-1-yl)cyclohexyl]-4-aminopyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl]-1-methylindole-2-carboxamide
- N-[4-[1-[trans-4-(4-Acetyl-1-piperazinyl)cyclohexyl]-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl]-1-methyl-1H-indole-2-carboxamide
- N-(4-(1-((1r,4r)-4-(4-acetylpiperazin-1-yl)cyclohexyl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide
- A-770041