MN 64
|
|
- CAS号:
- 92831-11-3
- 英文名:
- 2-(4-Isopropylpheny)-4H-chroMen-4-one
- 英文别名:
- MN-64;MN64, >98%;MN64; MN 64;2-(4-Isopropyl-phenyl)-chromen-4-one;2-(4-Propan-2-ylphenyl)chromen-4-one;2-(4-Isopropylpheny)-4H-chroMen-4-one;2-[4-(1-Methylethyl)phenyl]-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 2-[4-(1-methylethyl)phenyl]-;MN-64,MN 64,poly ADP ribose polymerase,Inhibitor,PARP,inhibit;2-(4-Isopropyl pheny)-4H-chromen-4-one,(flavone, LXR agonist)
- 中文名:
- MN 64
- 中文别名:
- 化合物MN64;TANKYRASES抑制剂(MN-64);2-(4-异丙基苯基)-4H-色烯-4-酮;2-(4-异丙基苯基)-4H-苯并吡喃-4-酮
- CBNumber:
- CB72719624
- 分子式:
- C18H16O2
- 分子量:
- 264.32
- MOL File:
- 92831-11-3.mol
|
|
|
MN 64化学性质
-
熔点:
-
63-64 °C(Solv: ethanol (64-17-5))
-
|
-
沸点:
-
389.8±42.0 °C(Predicted)
-
|
-
密度:
-
1.152±0.06 g/cm3(Predicted)
-
|
-
储存条件:
-
2-8°C
-
|
-
溶解度:
-
DMSO: soluble20mg/mL, clear
-
|
-
形态:
-
powder
-
|
-
颜色:
-
white to beige
-
|
MN 64性质、用途与生产工艺
MN-64是有效的TNKS1和TNKS2抑制剂,IC50分别为6 nM和72 nM。
Target | Value |
TNKS1
()
|
6 nM
|
TNKS2
()
|
72 nM
|
MN-64 is a potent tankyrase 1 inhibitor, with IC
50
s of 6 nM, 72 nM, 19.1 μM, 39.4 μM for TNKS1, TNKS2, ARTD1 and ARTD2, respectively. MN-64 effectively inhibits Wnt/β-catenin at 1 μM, and blocks STF luciferase activity at 200 nM.
MN 64
上下游产品信息
上游原料
下游产品
更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
---|
2024/08/19 | HY-19351 | MN 64 MN-64 | 92831-11-3 | 5mg | 450元 |
2024/08/19 | HY-19351 | MN 64 MN-64 | 92831-11-3 | 10mM * 1mLin DMSO | 495元 |
92831-11-3, MN 64 相关搜索:
- 药靶配体
- 细胞生物学试剂
- 精细化学品
- 药品
- 2-(4-异丙基苯基)-4H-苯并吡喃-4-酮
- 2-(4-异丙基苯基)-4H-色烯-4-酮
- 化合物MN64
- TANKYRASES抑制剂(MN-64)
- 92831-11-3
- MN-64,MN 64,poly ADP ribose polymerase,Inhibitor,PARP,inhibit
- 2-(4-Isopropyl pheny)-4H-chromen-4-one,(flavone, LXR agonist)
- MN64; MN 64
- 2-(4-Isopropyl-phenyl)-chromen-4-one
- MN64, >98%
- 4H-1-Benzopyran-4-one, 2-[4-(1-methylethyl)phenyl]-
- 2-[4-(1-Methylethyl)phenyl]-4H-1-benzopyran-4-one
- 2-(4-Isopropylpheny)-4H-chroMen-4-one
- 2-(4-Propan-2-ylphenyl)chromen-4-one
- MN-64