网站主页 >> CAS数据库列表 >> N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide
N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide
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- CAS号:
- 1292285-54-1
- 英文名:
- N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide
- 英文别名:
- SPRi 3;SPR inhibitor 3;N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide;Acetamide, N-[2-(5-hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxy-
- 中文名:
- N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide
- 中文别名:
- 化合物 T16924;N-[2-(5-羟基-2-甲基-1H-吲哚-3-基)乙基]-2-甲氧基乙酰胺
- CBNumber:
- CB74902897
- 分子式:
- C14H18N2O3
- 分子量:
- 262.3
- MOL File:
- 1292285-54-1.mol
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N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide化学性质
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沸点:
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561.9±50.0 °C(Predicted)
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密度:
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1.241±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO: 100 mM,Ethanol: 100 mM
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形态:
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A solid
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酸度系数(pKa):
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10.14±0.40(Predicted)
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颜色:
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Off-white to gray
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N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide性质、用途与生产工艺
SPR inhibitor 3 (SPRi3) 是一种有效的 sepiapertin 还原酶 (SPR) 抑制剂。SPR inhibitor 3 (SPRi3) 在非细胞体系中显示出与人 SPR 的高结合亲和力 (IC50=74 nM),在细胞检测中有效降低生物喋呤水平 (IC50=5.2 μM)。SPR inhibitor 3 (SPRi3) 通过降低 BH4 水平减少神经性和炎症性疼痛。
IC50: 74 nM (sepiapterin reductase)
SPR inhibitor 3 (SPRi3) also significantly reduces SPR activity in mouse primary cultures of sensory neurons (IC
50
=0.45 μM) without affecting the activity of GTP cyclohydroxylase 1 enzyme (GCH1).
N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide
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下游产品
更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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2024/04/30 | HY-115510 | N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide SPR inhibitor 3 | 1292285-54-1 | 5 mg | 1300元 |
2024/04/30 | HY-115510 | N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide SPR inhibitor 3 | 1292285-54-1 | 10mM * 1mLin DMSO | 1430元 |
N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide
生产厂家
1292285-54-1, N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide 相关搜索:
- N-[2-(5-羟基-2-甲基-1H-吲哚-3-基)乙基]-2-甲氧基乙酰胺
- 化合物 T16924
- 1292285-54-1
- Acetamide, N-[2-(5-hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxy-
- SPRi 3
- SPR inhibitor 3
- N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide