SPASTAZOLINE
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- CAS号:
- 2351882-11-4
- 英文名:
- Spastazoline
- 英文别名:
- Spastazoline;(R)-N-(5-(tert-Butyl)-1H-pyrazol-3-yl)-2-(3-isopropylpiperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine;HeLa,microtubule-severing,Inhibitor,inhibit,division,vesicle transport,Spastazoline,cell division,AAA protein,selective;7H-Pyrrolo[2,3-d]pyrimidin-4-amine, N-[5-(1,1-dimethylethyl)-1H-pyrazol-3-yl]-2-[(3R)-3-(1-methylethyl)-1-piperazinyl]-
- 中文名:
- SPASTAZOLINE
- 中文别名:
- 化合物SPASTAZOLINE;(R)-N-(5-(叔丁基)-1H-吡唑-3-基)-2-(3-异丙基哌嗪-1-基)-7H-吡咯并[2,3-D]嘧啶-4-胺
- CBNumber:
- CB74918009
- 分子式:
- C20H30N8
- 分子量:
- 382.51
- MOL File:
- 2351882-11-4.mol
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SPASTAZOLINE化学性质
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密度:
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1.222±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO : 100 mg/mL (261.43 mM; Need ultrasonic)
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形态:
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Solid
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酸度系数(pKa):
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14.26±0.50(Predicted)
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SPASTAZOLINE性质、用途与生产工艺
Spastazoline 是一种有效的、细胞可渗透的 spastin (a microtubule-severing AAA (ATPases associated with diverse cellular activities) protein) 的选择性抑制剂，对人类spastin的IC50值为99 nM。Spastazoline 不会抑制重组人VPS4 (胞间桥拆卸所需要的另一种AAA蛋白)的ATPase活性。
| Target | Value |
Human spastin
(Cell-free assay)
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99 nM
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SPASTAZOLINE
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/11/08 | HY-111548 | Spastazoline | | 1 mg | 636元 |
| 2024/11/08 | HY-111548 | SPASTAZOLINE
Spastazoline | 2351882-11-4 | 5mg | 1400元 |
2351882-11-4, SPASTAZOLINE 相关搜索:
- 抑制剂
- (R)-N-(5-(叔丁基)-1H-吡唑-3-基)-2-(3-异丙基哌嗪-1-基)-7H-吡咯并[2,3-D]嘧啶-4-胺
- 化合物SPASTAZOLINE
- 2351882-11-4
- HeLa,microtubule-severing,Inhibitor,inhibit,division,vesicle transport,Spastazoline,cell division,AAA protein,selective
- (R)-N-(5-(tert-Butyl)-1H-pyrazol-3-yl)-2-(3-isopropylpiperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, N-[5-(1,1-dimethylethyl)-1H-pyrazol-3-yl]-2-[(3R)-3-(1-methylethyl)-1-piperazinyl]-
- Spastazoline