AG 2263
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- CAS号:
- 638213-98-6
- 英文名:
- AG 2263
- 英文别名:
- AG 2263;AGL 2263;AGL 2263,AGL2263;Benzenepropanenitrile, α-[(2,3-dihydro-2-oxo-5-benzoxazolyl)methylene]-3,4-dihydroxy-β-oxo-, (αE)-
- 中文名:
- AG 2263
- 中文别名:
- 化合物 T14142;化合物 AGL-2263
- CBNumber:
- CB7828124
- 分子式:
- C17H10N2O5
- 分子量:
- 322.27
- MOL File:
- 638213-98-6.mol
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AG 2263化学性质
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熔点:
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210 °C
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密度:
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1.541±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 2 mg/ml
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形态:
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A crystalline solid
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酸度系数(pKa):
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7.47±0.20(Predicted)
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颜色:
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Light yellow to yellow
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AG 2263性质、用途与生产工艺
AGL-2263 是胰岛素受体 (insulin receptor) 和胰岛素样生长因子受体 (insulin-like growth factor (IGF) receptor) 的抑制剂。
AGL-2263 (5 μM, for 1 h followed by insulin treatment for 24 h) inhibits IR and insulin could still induce phosphorylation of AKT and ERK1/2 after the IR inhibition.
Western Blot Analysis
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Cell Line:
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Granulosa cells.
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Concentration:
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5 μM.
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Incubation Time:
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For 1 h followed by insulin treatment for 24 h.
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Result:
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Insulin still induced phosphorylation of AKT and ERK1/2 after IR was inhibited by AGL2263.
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AG 2263
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/11/08 | HY-112720 | AG 2263
AGL-2263 | 638213-98-6 | 5mg | 1500元 |
| 2024/11/08 | HY-112720 | AG 2263
AGL-2263 | 638213-98-6 | 10mM * 1mLin DMSO | 1560元 |
638213-98-6, AG 2263 相关搜索:
- 抑制剂
- 化合物 AGL-2263
- 化合物 T14142
- 638213-98-6
- AGL 2263,AGL2263
- Benzenepropanenitrile, α-[(2,3-dihydro-2-oxo-5-benzoxazolyl)methylene]-3,4-dihydroxy-β-oxo-, (αE)-
- AG 2263
- AGL 2263