美洛西林钠
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- CAS号:
- 42057-22-7
- 英文名:
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-6-[[[[[3-(methylsulfonyl)-2-oxo-1-imidazolidinyl]carbonyl]amino]phenylacetyl]amino]-7-oxo-, monosodium salt, [2S-[2alpha,5alpha,6beta(S*)]]-
- 英文别名:
- Baypen;Baycipen;Einecs 255-640-5;Monosodium mezlocillin;Mezlocillin sodum salt;Mezlocillin Sodium (1443307);Mezlocillin Sodium, 10 mM in DMSO;Sodium (2S,5R,6R)-3,3-dimethyl-6-((R)-2-(3-(methylsulfonyl)-2-oxoimidazolidine-1-carboxamido)-2-phenylacetamido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;(2S,5β)-3,3-Dimethyl-6α-[[(R)-[[[3-(methylsulfonyl)-2-oxo-1-imidazolidinyl]carbonyl]amino]phenylacetyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid sodium salt;4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-6-(((2R)-(((3-(methylsulfonyl)-2-oxo-1-imidazolidinyl)carbonyl)amino)phenylacetyl)amino)-7-oxo-, monosodium salt, (2S,5R,6R)-
- 中文名:
- 美洛西林钠
- 中文别名:
- 美洛西林钠,10 MM DMSO 溶液;(2S,5R,6R)-3,3-二甲基-6-[[(2R)-2-[[[3-(甲基磺酰基)-2-氧代-1-咪唑啉基]羰基]氨基]-2-苯基乙酰基]氨基]-7-氧代-4-硫杂-1-氮杂双环[3.2.0]庚烷-2-羧酸钠盐
- CBNumber:
- CB7898307
- 分子式:
- C21H26N5NaO8S2
- 分子量:
- 563.58
- MOL File:
- 42057-22-7.mol
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美洛西林钠化学性质
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储存条件:
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2-8°C
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溶解度:
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DMSO: soluble1mg/mL
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形态:
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Solid
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颜色:
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white
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美洛西林钠性质、用途与生产工艺
Mezlocillin Sodium是青霉素的beta-内酰胺类抗生素，通常用于治疗革兰氏阳性菌引起的感染。
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beta-lactamase
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Mezlocillin sodium具有对革兰氏阳性、革兰氏阴性需氧和厌氧细菌的体外抗菌活性。mezlocillin抑制细胞壁合成而具有杀菌活性，该过程由mezlocillin与青霉素结合蛋白（PBPs）介导。Mezlocillin对各种β-内酰胺酶，包括青霉素酶、头孢菌素酶和广谱β-内酰胺酶引起的水解都是稳定的。Mezlocillin结合到位于细菌细胞壁内特定的青霉素结合蛋白（PBPs）上，从而抑制细菌细胞壁合成的第三阶段和最后阶段。随后在细菌细胞壁自溶酶，如自溶素作用下，细胞裂解；这可能是由于Mezlocillin干扰了自溶素抑制剂。与其它许多青霉素不同，mezlocillin广泛代谢或由胆汁排泄，只有约50％的剂量出现在正常尿液中。
美洛西林钠
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2025/02/05 | S4179 | 美洛西林钠
Mezlocillin Sodium | 42057-22-7 | 50mg | 798.28元 |
42057-22-7, 美洛西林钠 相关搜索:
- Inhibitors
- 抑制剂
- 药靶配体
- 化学试剂
- 小分子抑制剂，天然产物
- C21H25N5O8S2Na
- 美洛西林钠,10 MM DMSO 溶液
- (2S,5R,6R)-3,3-二甲基-6-[[(2R)-2-[[[3-(甲基磺酰基)-2-氧代-1-咪唑啉基]羰基]氨基]-2-苯基乙酰基]氨基]-7-氧代-4-硫杂-1-氮杂双环[3.2.0]庚烷-2-羧酸钠盐
- 42057-22-7
- Mezlocillin Sodium, 10 mM in DMSO
- Mezlocillin sodum salt
- Sodium (2S,5R,6R)-3,3-dimethyl-6-((R)-2-(3-(methylsulfonyl)-2-oxoimidazolidine-1-carboxamido)-2-phenylacetamido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
- Mezlocillin Sodium (1443307)
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,3,3-dimethyl-6-[[[[[3-(methylsulfonyl)-2-oxo-1-imChemicalbookidazolidinyl]carbonyl]amino]phenylacetyl]amino]-7-oxo-,monosodiumsalt,[2S-[2alpha,5alpha,6beta(S*)]]- USP/EP/BP
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-6-[[(2R)-2-[[[3-(methylsulfonyl)-2-oxo-1-imidazolidinyl]carbonyl]amino]-2-phenylacetyl]amino]-7-oxo-, sodium salt (1:1), (2S,5R,6R)-
- Monosodium mezlocillin
- Einecs 255-640-5
- Baypen
- Baycipen
- 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-6-(((2R)-(((3-(methylsulfonyl)-2-oxo-1-imidazolidinyl)carbonyl)amino)phenylacetyl)amino)-7-oxo-, monosodium salt, (2S,5R,6R)-
- 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-6-(((((3-(methylsulfonyl)-2-oxo-1-imidazolidinyl)carbonyl)amino)phenylacetyl)amino)-7-oxo-, monosodium salt, (2S-(2alpha,5alpha,6beta(S*)))-
- (2S,5β)-3,3-Dimethyl-6α-[[(R)-[[[3-(methylsulfonyl)-2-oxo-1-imidazolidinyl]carbonyl]amino]phenylacetyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid sodium salt
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-6-[[[[[3-(methylsulfonyl)-2-oxo-1-imidazolidinyl]carbonyl]amino]phenylacetyl]amino]-7-oxo-, monosodium salt, [2S-[2alpha,5alpha,6beta(S*)]]-