symphytine
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- CAS号:
- 22571-95-5
- 英文名:
- symphytine
- 英文别名:
- symphytine;2-Butenoic acid, 2-methyl-, (1R,7aR)-7-[[(2S,3S)-2,3-dihydroxy-2-(1-methylethyl)-1-oxobutoxy]methyl]-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-yl ester, (2E)-
- 中文名:
- symphytine
- 中文别名:
- 西门肺草碱
- CBNumber:
- CB81328383
- 分子式:
- C20H31NO6
- 分子量:
- 381.46
- MOL File:
- 22571-95-5.mol
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symphytine化学性质
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沸点:
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508.85°C (rough estimate)
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密度:
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1.2168 (rough estimate)
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折射率:
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1.5614 (estimate)
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酸度系数(pKa):
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12.59±0.29(Predicted)
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(IARC)致癌物分类:
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3 (Vol. 31, Sup 7) 1987
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symphytine性质、用途与生产工艺
Symphytine 从 Symphytum officinale 中分离出来一种吡啶生物碱，具有致癌性。
Symphytine (intraperitoneal injection; 13 mg/kg; 330 days) leads to survival for more than 330 days after the start of injections. Four of 20 rats (20%) had liver tumors: three has hemangioendothelial sarcoma and 1 has liver cell adenoma.
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Animal Model:
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Male inbred ACI rats
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Dosage:
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13 mg/kg
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Administration:
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Intraperitoneal injection; 330 days
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Result:
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Led to hepatic tumor in rats.
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symphytine
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22571-95-5, symphytine 相关搜索:
- 对照品
- C20H31NO6
- 西门肺草碱
- 22571-95-5
- 2-Butenoic acid, 2-methyl-, (1R,7aR)-7-[[(2S,3S)-2,3-dihydroxy-2-(1-methylethyl)-1-oxobutoxy]methyl]-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-yl ester, (2E)-
- symphytine