(4E)-TCO-PEG4-DBCO
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- CAS号:
- 1801863-88-6
- 英文名:
- (4E)-TCO-PEG4-DBCO
- 英文别名:
- TCO-PEG4-DBCO;(4E)-TCO-PEG4-DBCO
- 中文名:
- (4E)-TCO-PEG4-DBCO
- 中文别名:
- 反式环辛烯-四聚乙二醇-二苯并环辛炔;(4E)-反式环辛烯-四聚乙二醇-二苯并环辛炔;(4E)-反式环辛烯-四聚乙二醇-二苯基环辛炔;反式环辛烯-四聚乙二醇-二苯基环辛炔,TCO-PEG4-DBCO
- CBNumber:
- CB84849386
- 分子式:
- C38H49N3O8
- 分子量:
- 675.82
- MOL File:
- 1801863-88-6.mol
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(4E)-TCO-PEG4-DBCO化学性质
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沸点:
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891.1±65.0 °C(Predicted)
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密度:
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1.22±0.1 g/cm3(Predicted)
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溶解度:
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Soluble in Partially Water Soluble, DMSO, DCM, DMF
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酸度系数(pKa):
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11.95±0.46(Predicted)
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形态:
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Oil
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颜色:
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Colorless to light yellow
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(4E)-TCO-PEG4-DBCO性质、用途与生产工艺
TCO-PEG4-DBCO 是一种 PROTAC 连接桥，属于 PEG 类。TCO-PEG4-DBCO 可用于合成一系列 PROTAC 分子。TCO-PEG4-DBCO 是一种可降解 (cleavable) 的 ADC 连接桥，用于抗体药物结合物 (ADCs) 的合成。
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
(4E)-TCO-PEG4-DBCO
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1801863-88-6, (4E)-TCO-PEG4-DBCO 相关搜索:
- ADC LINKER
- C38H49N3O8
- 反式环辛烯-四聚乙二醇-二苯并环辛炔
- (4E)-反式环辛烯-四聚乙二醇-二苯并环辛炔
- (4E)-反式环辛烯-四聚乙二醇-二苯基环辛炔
- 反式环辛烯-四聚乙二醇-二苯基环辛炔,TCO-PEG4-DBCO
- 1801863-88-6
- TCO-PEG4-DBCO
- (4E)-TCO-PEG4-DBCO