CYN 154806 TFA
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- CAS号:
- 英文名:
- CYN 154806 TFA
- 英文别名:
- CYN 154806 TFA
- 中文名:
- CYN 154806 TFA
- 中文别名:
- 环状八肽AC-PHE-CYS-TYR-TRP-LYS-THR-CYS-TYR-NH2
- CBNumber:
- CB85419720
- 分子式:
- C??H??F?N??O??S?
- 分子量:
- 0
- MOL File:
- Mol file
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CYN 154806 TFA化学性质
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序列:
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Ac-Phe-Cys-Tyr-Trp-Lys-Thr-Cys-Tyr-NH2?(Disulfide?bridge:?Cys2-Cys7)
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CYN 154806 TFA性质、用途与生产工艺
CYN 154806 TFA 是一种环状八肽，是一种强效的，选择性生长抑素 sst2 受体的拮抗剂，其对人重组 sst2、sst1、sst3、sst4 和 sst5 受体的 pIC50 值分别为 8.58、5.41、6.07、5.76 和 6.48。
CYN 154806 TFA inhibits SRIF-induced increases in extracellular acidification (EAR) in CHO-K1 cells expressing human sst2 receptors (pKB 7.92). CYN 154806 TFA also blocks SRIF-induced increases [35S]-GTPγS binding in CHO-K1 cell membranes expressing human sst2 receptors as well as rat sst2(a) and rat sst2(b) receptors (pKB 7.81, 7.68 and 7.96, respectively).
CYN 154806 TFA (0.1 mg/kg; i.p.; 20 min before the administration of carbachol (CCh) (30 μg/kg) in M4 KO mice) dose-dependently and significantly reverses the decreases acid response to CCh in M4 but not M3 KO mice.
参考质量标准
外观:白色粉末
纯度(HPLC) ≥98.0%
醋酸根含量≤12.0%
水分含量≤8.0%
肽含量≥80.0%
内毒素≤50EU/mg
氨基酸组成分析≤±10%
CYN 154806 TFA
上下游产品信息
上游原料
下游产品
CYN 154806 TFA 试剂级价格
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/11/08 | HY-P1202A | CYN 154806 TFA
CYN 154806 TFA | | 1mg | 1800元 |
| 2024/11/08 | HY-P1202A | CYN 154806 TFA
CYN 154806 TFA | | 5mg | 3800元 |
CYN 154806 TFA 相关搜索:
- 目录多肽
- 环状八肽AC-PHE-CYS-TYR-TRP-LYS-THR-CYS-TYR-NH2
- CYN 154806 TFA