氢化奎宁-9-菲基醚
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- CAS号:
- 135096-78-5
- 英文名:
- HYDROQUININE 9-PHENANTHRYL ETHER
- 英文别名:
- O-(9-PHENANTHRYL)HYDROQUININE;HYDROQUININE 9-PHENANTHRYL ETHER;Hydroquinine-9-phenanthryl ether 97%;(8α,9R)-10,11-Dihydro-6'-methoxy-9-(9-phenanthrenyloxy)cinchonan;(8α,9R)-10,11-Dihydro-6'-methoxy-9-(9-phenanthrenyloxy)cinchonan;(8α,9R)-10,11-dihydro-6'-Methoxy-9-(9-phenanthrenyloxy)-Cinchonan;Cinchonan, 10,11-dihydro-6'-Methoxy-9-(9-phenanthrenyloxy)-, (8α,9R)-;(2S,4S,5R)-5-Ethyl-2-((R)-(6-methoxyquinolin-4-yl)(phenanthren-9-yloxy)methyl)quinuclidine
- 中文名:
- 氢化奎宁-9-菲基醚
- 中文别名:
- 氢化奎宁-9-菲基醚;O-(9-菲基)氢化奎宁;(8Α,9R)-10,11-二氢-6'-甲氧基-9-(9-菲基氧基)奎宁;(8Α,9R)-10,11-二氢-6'-甲氧基-9-(9-菲基氧基)奎宁;(2S,4S,5R)-5-乙基-2-((R)-(6-甲氧基喹啉-4-基)(菲-9-基氧基)甲基)奎宁环
- CBNumber:
- CB8744726
- 分子式:
- C34H34N2O2
- 分子量:
- 502.65
- MOL File:
- 135096-78-5.mol
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氢化奎宁-9-菲基醚化学性质
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熔点:
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120 °C (dec.)(lit.)
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沸点:
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690.3±40.0 °C(Predicted)
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密度:
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1.24±0.1 g/cm3(Predicted)
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储存条件:
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under inert gas (nitrogen or Argon) at 2-8°C
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酸度系数(pKa):
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9?+-.0.70(Predicted)
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旋光性 (optical activity):
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[α]20/D +420°, c = 1 in ethanol
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BRN:
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4848702
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氢化奎宁-9-菲基醚性质、用途与生产工艺
氢化奎宁属喹琳生物碱类化合物。易溶于热乙醇，微溶于水和乙醚，其盐酸盐为小片状结晶，易溶于甲醇、氯仿，微溶于水或乙醇，难溶于醋酸。为抗心律失常药，作用与奎尼丁相仿，口服毒性稍低于奎尼丁。
氢化奎尼定也是以一种重要的医药中间体，但是目前对于其制备方法报道较少，现有的方法产品收率较低，且制备成本高。氢化奎宁-9-菲基醚为一种新颖的氢化奎尼定属喹琳生物碱类化合物。
氢化奎宁-9-菲基醚
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135096-78-5, 氢化奎宁-9-菲基醚 相关搜索:
- Asymmetric Synthesis
- Chiral Catalysts, Ligands, and Reagents
- Cinchona Alkaloids
- Privileged Ligands
- C34H34N2O2
- (8Α,9R)-10,11-二氢-6'-甲氧基-9-(9-菲基氧基)奎宁
- (8Α,9R)-10,11-二氢-6'-甲氧基-9-(9-菲基氧基)奎宁
- (2S,4S,5R)-5-乙基-2-((R)-(6-甲氧基喹啉-4-基)(菲-9-基氧基)甲基)奎宁环
- O-(9-菲基)氢化奎宁
- 氢化奎宁-9-菲基醚
- 135096-78-5
- (8α,9R)-10,11-Dihydro-6'-methoxy-9-(9-phenanthrenyloxy)cinchonan
- (8α,9R)-10,11-Dihydro-6'-methoxy-9-(9-phenanthrenyloxy)cinchonan
- (2S,4S,5R)-5-Ethyl-2-((R)-(6-methoxyquinolin-4-yl)(phenanthren-9-yloxy)methyl)quinuclidine
- (8α,9R)-10,11-dihydro-6'-Methoxy-9-(9-phenanthrenyloxy)-Cinchonan
- Cinchonan, 10,11-dihydro-6'-Methoxy-9-(9-phenanthrenyloxy)-, (8α,9R)-
- Hydroquinine-9-phenanthryl ether 97%
- HYDROQUININE 9-PHENANTHRYL ETHER
- O-(9-PHENANTHRYL)HYDROQUININE