TGR5
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- CAS号:
- 1197300-24-5
- 英文名:
- 4-IsoxazolecarboxaMide, 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-diMethyl-
- 英文别名:
- CCDC;TGR5;CS-1017;MDK00245;TGR5 Receptor Agonist;CCDC(TGR5-Receptor-Agonist);TGR5 Receptor Agonist, >=98%;TGR5 Receptor Agonist(isoxazole);BENZYL (4-CHLORO-1H-PYRROLO[2,3-B]PYRIDIN-1-YL)ACETATE;3-(2-CHLOROPHENYL)-N-(4-CHLOROPHENYL)-N,5-DIMETHYLISOXAZOLE-4-CARBOXAMIDE
- 中文名:
- TGR5
- 中文别名:
- 化合物TGR5;TGR5受体激动剂;TGR5 G蛋白受体激动剂;化合物 TGR5 RECEPTOR AGONIST;3-(2-氯苯基)-N-(4-氯苯基)-N,5-二甲基异恶唑-4-甲酰胺;3-(2-氯苯基)-N-(4-氯苯基)-N,5-二甲基-4-异噁唑羧酰胺;3-(2-氯苯基)-N-(4-氯苯基)-N,5-二甲基-4-异恶唑甲酰胺
- CBNumber:
- CB92627077
- 分子式:
- C18H14Cl2N2O2
- 分子量:
- 361.22
- MOL File:
- 1197300-24-5.mol
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TGR5化学性质
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沸点:
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541.8±50.0 °C(Predicted)
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密度:
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1.346±0.06 g/cm3(Predicted)
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储存条件:
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2-8°C
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溶解度:
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DMF: 50 mg/ml; DMSO: 50 mg/ml; DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml; Ethanol: 30 mg/ml
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形态:
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A crystalline solid
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酸度系数(pKa):
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-0.52±0.50(Predicted)
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颜色:
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White to off-white
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TGR5性质、用途与生产工艺
TGR5 Receptor Agonist (CCDC) 是 TGR5(GPCR19) 激动剂。
IC50 value: 6.8 (pEC
50
, U2-OS cell assay); 7.5 (pEC
50
, melanophore cell)
TGR5
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/11/08 | HY-14229 | TGR5
TGR5 Receptor Agonist | 1197300-24-5 | 5mg | 900元 |
| 2024/11/08 | HY-14229 | TGR5
TGR5 Receptor Agonist | 1197300-24-5 | 10mM * 1mLin DMSO | 990元 |
1197300-24-5, TGR5 相关搜索:
- Inhibitors
- 抑制剂
- 药靶配体
- 小分子抑制剂，天然产物
- 小分子抑制剂
- 化合物 TGR5 RECEPTOR AGONIST
- TGR5受体激动剂
- 3-(2-氯苯基)-N-(4-氯苯基)-N,5-二甲基异恶唑-4-甲酰胺
- 化合物TGR5
- TGR5 G蛋白受体激动剂
- 3-(2-氯苯基)-N-(4-氯苯基)-N,5-二甲基-4-异噁唑羧酰胺
- 3-(2-氯苯基)-N-(4-氯苯基)-N,5-二甲基-4-异恶唑甲酰胺
- 1197300-24-5
- TGR5 Receptor Agonist(isoxazole)
- 3-(2-Chlorophenyl)-N-(4-chlorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
- MDK00245
- CS-1017
- CCDC(TGR5-Receptor-Agonist)
- BENZYL (4-CHLORO-1H-PYRROLO[2,3-B]PYRIDIN-1-YL)ACETATE
- CCDC
- TGR5 Receptor Agonist, >=98%
- TGR5 4-IsoxazolecarboxaMide, 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-diMethyl-
- 3-(2-Chlorophenyl)-N-(4-chlorophenyl)-N,5-dimethyl-4-isoxazolecarboxamide TGR5
- 3-(2-CHLOROPHENYL)-N-(4-CHLOROPHENYL)-N,5-DIMETHYLISOXAZOLE-4-CARBOXAMIDE
- TGR5 Receptor Agonist
- 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-diMethyl-4-IsoxazolecarboxaMide
- TGR5
- 4-IsoxazolecarboxaMide, 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-diMethyl-