荧光标记淀粉样蛋白肽(1-40)
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- CAS号:
- 1678416-08-4
- 英文名:
- 5-FAM-Amyloid β-Protein (1-40)
- 英文别名:
- β-Amyloid (1-40), FAM-labeled;5-FAM-Amyloid β-Protein (1-40);5-FAM-Amyloid β-Protein (1-40);5-FAM-Amyloid β-Protein (1-40) trifluoroacetate salt
- 中文名:
- 荧光标记淀粉样蛋白肽(1-40)
- 中文别名:
- 荧光标记淀粉样蛋白肽(1-40)
- CBNumber:
- CB93158644
- 分子式:
- 分子量:
- 0
- MOL File:
- Mol file
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荧光标记淀粉样蛋白肽(1-40)性质、用途与生产工艺
β-Amyloid (1-40), FAM-labeled 是一个 FAM 荧光标记的 β-Amyloid (1-40) 肽 (λex= 492 nm and λem= 518 nm)。
λ
ex
= 492 nm; λ
em
= 518 nm
Apical-to-basolateral exchange across endothelial monolayer of fluorescent Aβ42 (FAM-labeled Human β-Amyloid (1-42) and Fluor
™
488-labeled β-Amyloid (1-42)) or scramble Aβ42 (
FAM-labeled scrambled β-Amyloid (1-42)
) (1-100 μM) is monitored in transendothelial electrical resistance (TEER) during cell monolayer’s formation over time (over 120 min in presence or absence of Aβ24). Human β-Amyloid (1-24) (1 μM) results in H-Aβ42 retention, thus reducing its efflux through the BBB and therefore preventing an efficient mechanism of Aβ42 clearance.The in vitro BBB model is used to investigate the passage of FAM-labeled or 488-conjugated H-Aβ42 across the endothelial cell monolayer. The addition of fluorescently labeled H-Aβ42 (FAM-labeled Human β-Amyloid (1-42) or Fluor
™
488-labeled β-Amyloid (1-42)) to the apical side of cell inserts results in effective BBB crossing, FAM-labeled scrambled β-Amyloid (1-42) is not efficiently transcytosed.
荧光标记淀粉样蛋白肽(1-40)
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1678416-08-4, 荧光标记淀粉样蛋白肽(1-40) 相关搜索:
- 多肽
- 目录肽
- 荧光标记淀粉样蛋白肽(1-40)
- 1678416-08-4
- 5-FAM-Amyloid β-Protein (1-40)
- 5-FAM-Amyloid β-Protein (1-40) trifluoroacetate salt
- β-Amyloid (1-40), FAM-labeled
- 5-FAM-Amyloid β-Protein (1-40)