网站主页 >> CAS数据库列表 >> 1,4-二氢-2,6-二甲基-5-硝基-4-(2-[三氟甲基]苯基)吡啶-3-羧酸甲酯
1,4-二氢-2,6-二甲基-5-硝基-4-(2-[三氟甲基]苯基)吡啶-3-羧酸甲酯
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- CAS号:
- 71145-03-4
- 英文名:
- (+/-)-BAY K 8644
- 英文别名:
- SQ-28873;(RS)-BAY K 8644;BAY K-8644 (+/-);(+/-)-BAY K 8644;(+/-)-BAY K 8644;(±)-Bay K 8644,98%;BAYK 8644 (racemate);BAYK 8644; BAYK8644; BAYK-8644;(+/-)-BAY K8644 CALCIUM SLOW CHANNEL;(+/-)-Bay K8644 calcium channel agonist
- 中文名:
- 1,4-二氢-2,6-二甲基-5-硝基-4-(2-[三氟甲基]苯基)吡啶-3-羧酸甲酯
- 中文别名:
- 氟硝尼啶;API,氟硝尼啶;BAY K 8644游离;化合物BAY K 8644;(±)-BAYK8644,L型CA 2+通道激活剂;(±)-BAYK8644,L-TYPE CA2+ CHANNEL活化剂;2,6-二甲基-5-硝基-4-(2-(三氟甲基)苯基)-1,4-二氢吡啶-3-羧酸甲酯;1,4-二氢-2,6-二甲基-5-硝基-4-(2-[三氟甲基]苯基)吡啶-3-羧酸甲酯
- CBNumber:
- CB9471784
- 分子式:
- C16H15F3N2O4
- 分子量:
- 356.3
- MOL File:
- 71145-03-4.mol
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1,4-二氢-2,6-二甲基-5-硝基-4-(2-[三氟甲基]苯基)吡啶-3-羧酸甲酯化学性质
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熔点:
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166 °C
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沸点:
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429.2±45.0 °C(Predicted)
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密度:
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1.3548 (estimate)
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RTECS号:
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US5655000
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储存条件:
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2-8°C
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溶解度:
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DMSO: 184 mg/mL
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酸度系数(pKa):
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-3.43±0.70(Predicted)
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形态:
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Yellow solid.
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颜色:
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Yellow
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水溶解性:
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Soluble in DMSO at 20mg/ml. Also soluble in methanol or ethanol at 60mg/ml. Insoluble in water
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稳定性:
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Stable. Incompatible with strong oxidizing agents.
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1,4-二氢-2,6-二甲基-5-硝基-4-(2-[三氟甲基]苯基)吡啶-3-羧酸甲酯性质、用途与生产工艺
BAY K8644 是一种L 型Ca
2+通道激活剂，具有正性肌力作用和血管收缩作用，可用作活性 L 型钙通道激动剂。
Bay K 8644是一种高选择性的L型钙离子通道激动剂，EC50为17.3 nM。
| Target | Value |
L-type calcium channel
(in the isolated field-stimulated vas deferens of the mouse)
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17.3nM(EC50)
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Bay K 8644 作为L型钙离子的激动剂，提高了取自大鼠的肠系膜动脉的静息张力。
Bay K 8644 可诱导5周龄、3月龄、1年、1.5年龄wistar-kyoto大鼠主动脉的小的收缩，这一现象不受大鼠年龄所影响。
1,4-二氢-2,6-二甲基-5-硝基-4-(2-[三氟甲基]苯基)吡啶-3-羧酸甲酯
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/11/08 | HY-10588 | Bay K 8644 | | 1 mg | 454元 |
| 2024/11/08 | HY-10588 | 1,4-二氢-2,6-二甲基-5-硝基-4-(2-[三氟甲基]苯基)吡啶-3-羧酸甲酯
Bay K 8644 | 71145-03-4 | 5mg | 1000元 |
1,4-二氢-2,6-二甲基-5-硝基-4-(2-[三氟甲基]苯基)吡啶-3-羧酸甲酯
生产厂家
71145-03-4, 1,4-二氢-2,6-二甲基-5-硝基-4-(2-[三氟甲基]苯基)吡啶-3-羧酸甲酯 相关搜索:
- Calcium channel
- 合成有机化合物配体
- 抑制剂
- Biochemicals and Reagents
- BioChemical
- Enzyme Inhibitors
- Enzyme Inhibitors by Type
- Enzymes, Inhibitors, and Substrates
- Substrate Analogs
- (±)-BAYK8644,L-TYPE CA2+ CHANNEL活化剂
- (±)-BAYK8644,L型CA 2+通道激活剂
- 化合物BAY K 8644
- BAY K 8644游离
- 2,6-二甲基-5-硝基-4-(2-(三氟甲基)苯基)-1,4-二氢吡啶-3-羧酸甲酯
- API,氟硝尼啶
- 氟硝尼啶
- 1,4-二氢-2,6-二甲基-5-硝基-4-(2-[三氟甲基]苯基)吡啶-3-羧酸甲酯
- 71145-03-4
- (±)-BAYK8644, L-type Ca2+ channel activator
- Methyl (R)-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridine-3-carboxylate
- Bay K8644,influx,L-type,inhibit,sarcolemmal,Ca2+ channels,(±)-Bay K 8644,Bay K-8644,Bay K 8644,Inhibitor,Ca channels,Ca2+,Calcium Channel
- (+/-)-BAY K 8644
- Methyl 2,6-dimethyl-3-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-5-carboxylate
- Methyl 2,6-dimethyl-3-nitro-4-[2-(trifluoromethyl)phenyl]-1,...
- BAYK 8644 (racemate)
- (+/-)-Bay K8644 calcium channel agonist
- BAYK 8644; BAYK8644; BAYK-8644
- (4R)-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylic acid methyl ester
- methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate
- (±)-Bay K 8644,98%
- SQ-28873
- (RS)-BAY K 8644
- 1,4-Dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-3-pyridinecarboxylicacidmethylester
- (+/-)-BAY K8644 CALCIUM SLOW CHANNEL
- 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-diMethyl-5-nitro-4-[2-(trifluoroMethyl)phenyl]-, Methyl ester
- BAY K-8644 (+/-)
- (+/-)-BAY K 8644
- 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-[TRIFLUOROMETHYL]PHENYL)PYRIDINE-3-CARBOXYLIC ACID METHYL ESTER
- 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID, METHYL ESTER
- 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2'-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID METHYL ESTER