2,6-Dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyridazin-1one

生物活性体外研究 2,6-Dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyridazin-1one 试剂级价格

CAS号:: 227321-12-2

英文名:: 2,6-Dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyridazin-1one

英文别名:: SR 13800;MCT1-IN-2;MCT-1-IN-2,MCT1 IN 2,MCT1IN2;2,6-Dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyridazin-1one;1H-Pyrrolo[3,4-d]pyridazin-1-one, 2,6-dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-

中文名:: 2,6-Dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyridazin-1one

中文别名:: 化合物 T26221;化合物 MCT1-IN-2;SR 13800,MCT1抑制剂

CBNumber:: CB94902679

分子式:: C25H29N3O2S

分子量:: 435.58

MOL File:: 227321-12-2.mol

化学性质安全信息用途价格供应商 21

2,6-Dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyridazin-1one化学性质

熔点:: 152 °C

沸点:: 642.8±65.0 °C(Predicted)

密度:: 1.23±0.1 g/cm3(Predicted)

储存条件:: Store at -20°C

溶解度:: Soluble in DMSO

形态:: Solid

酸度系数(pKa):: 14.87±0.10(Predicted)

颜色:: White to off-white

安全信息

2,6-Dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyridazin-1one性质、用途与生产工艺

生物活性

MCT1-IN-2 是有效的单羧酸盐转运蛋白 1 (MCT1) 抑制剂。MCT1-IN-2 具有抗癌活性。

MCT1-IN-2 (compound 3) has a pK _i of 9.48 for Jurkat T-cells and inhibits human peripheral blood mononuclear cells (PBMC) proliferation (pIC ₅₀ =8.61).
MCT1-IN-2 (compound 1) has an EC ₅₀ of 5.5 nM (MTT assay) and an IC ₅₀ of 105 nM (lactate transport inhibition assay) in human Raji lymphoma cell proliferation.

2,6-Dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyridazin-1one 上下游产品信息

上游原料

下游产品

2,6-Dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyridazin-1one 试剂级价格

更新日期	产品编号	产品名称	CAS编号	包装	价格
2024/08/19	HY-18974	2,6-Dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyridazin-1one MCT1-IN-2	227321-12-2	1mg	1900元
2024/08/19	HY-18974	2,6-Dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyridazin-1one MCT1-IN-2	227321-12-2	5mg	4200元

2,6-Dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyridazin-1one 生产厂家

全球有 21家供应商 2,6-Dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyridazin-1one国内生产厂家

供应商	联系电话	电子邮件	国家	产品数	优势度
上海瀚香生物科技有限公司	17754423994 17754423994	2853530910@QQ.com	中国	8014	62
上海宏叶生物科技有限公司	400-9205774	sales@glpbio.cn	中国	6870	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	美国	19892	58
天津普西唐生物医药科技有限公司	010-60605840 15801484223	psaitong@jm-bio.com	中国	29778	58
TargetMol中国（陶术生物）	4008200310	marketing@tsbiochem.com	中国	24648	58
郑州汇聚化工有限公司	0371-0371-53399770 18037166334	2853031800@qq.com	中国	3052	58
南通全益生物科技有限公司	0513-66337626 18051384581	sales@chemhifuture.com	中国	4738	58
上海合灵信德药物研究有限责任公司	021-61734564	August@easycdmo.com	中国	10010	58
上海阿拉丁生化科技股份有限公司	+86-18521732826	market@aladdin-e.com	中国	48465	58
銳迪國際科技有限公司	18024082417	market@ubiochem.com	中国	9268	58
山东东德新材料有限公司	15764055027	15764055027@163.com	中国	627	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	美国	57511	58

227321-12-2, 2,6-Dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyridazin-1one 相关搜索:

抑制剂
药靶配体
化合物 MCT1-IN-2
SR 13800,MCT1抑制剂
化合物 T26221
227321-12-2
1H-Pyrrolo[3,4-d]pyridazin-1-one, 2,6-dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-
MCT-1-IN-2,MCT1 IN 2,MCT1IN2
MCT1-IN-2
SR 13800
2,6-Dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyridazin-1one