(20S)-2,16-Didehydro-20-hydroxycuran-17-oic acid methyl ester

5980-01-8

CAS-Nr.: 5980-01-8

Englisch Name:: (20S)-2,16-Didehydro-20-hydroxycuran-17-oic acid methyl ester

Synonyma:: Lochneridine;(20S)-2,16-Didehydro-20-hydroxycuran-17-oic acid methyl ester;Curan-17-oic acid, 2,16-didehydro-20-hydroxy-, methyl ester, (20α)- (9CI)

CBNumber:: CB12187337

Summenformel:: C20H24N2O3

Molgewicht:: 340.42

MOL-Datei:: 5980-01-8.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 1

(20S)-2,16-Didehydro-20-hydroxycuran-17-oic acid methyl ester Eigenschaften

Schmelzpunkt:: 211-4°C (dec.).

Siedepunkt:: 507.7±50.0 °C(Predicted)

alpha: D26 +607.5° (chloroform)

Dichte: 1.34±0.1 g/cm3(Predicted)

pka: 5.5 in 66% DMF

Sicherheit

(20S)-2,16-Didehydro-20-hydroxycuran-17-oic acid methyl ester Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

A further alkaloid from Vinca rosea L., forming colourless prisms when crystallized from MeOH. The ultraviolet spectrum has absorption maxima at 230, 293 and 328 mil. The base contains a tertiary hydroxyl group and an imino group and, with AC20 in pyridine, furnishes akuammicine (q.v.), by dehydration. Reduction with Zn dust in MeOH-H2S04 yields 2: 16-dihydroakuammicine after preparative thin-layer chromatography on silica gel.

Einzelnachweise

Svoboda et al., J. Pharm. Sci., 50, 409 (1961)
Structure:
Nakagawa et at., Chem. Ind., 1986 (1962)

(20S)-2,16-Didehydro-20-hydroxycuran-17-oic acid methyl ester Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(20S)-2,16-Didehydro-20-hydroxycuran-17-oic acid methyl ester Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 1)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58

(20S)-2,16-Didehydro-20-hydroxycuran-17-oic acid methyl ester
Lochneridine
Curan-17-oic acid, 2,16-didehydro-20-hydroxy-, methyl ester, (20α)- (9CI)
5980-01-8
C20H24O3N2