Carebastine-d5

1189661-02-6

CAS-Nr.: 1189661-02-6

Englisch Name:: Carebastine-d5

Synonyma:: Carebastine-d5;Valine Impurity 136;4-[4-[4-(DiphenylMethoxy-d5)-1-piperidinyl]-1-oxobutyl]-α,α-diMethylbenzeneacetic Acid;4-[4-[4-(Diphenylmethoxy-d5)-1-piperidinyl]-1-oxobutyl]-a,a-dimethylbenzeneacetic Acid;4-[4-[4-(Diphenylmethoxy-d5)-1-piperidinyl]-1-oxobutyl]-α,a-dimethylbenzeneacetic Acid

CBNumber:: CB61565757

Summenformel:: C32H37NO4

Molgewicht:: 499.64048

MOL-Datei:: 1189661-02-6.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 25

Carebastine-d5 Eigenschaften

Schmelzpunkt:: 72-74°C

storage temp.: -20°C Freezer

Löslichkeit: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

Aggregatzustand: Solid

Farbe: Off-White to Light Yellow

Sicherheit

Carebastine-d5 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Carebastine-d₅ is intended for use as an internal standard for the quantification of carebastine by GC- or LC-MS. Carebastine is an active metabolite of ebastine and a histamine H₁ receptor antagonist (K_i = 75.86 nM). It inhibits histamine-induced contraction of isolated guinea pig trachea (IC₅₀ = 120 nM). It also inhibits histamine release from isolated rat peritoneal mast cells and human basophils when used at concentrations ranging from 30 to 100 μM. Carebastine decreases production of chemokine (C-C motif) ligand 5 (CCL5) and CCL2 in human nasal epithelial cells isolated from patients with nasal allergies.

Chemische Eigenschaften

Off-White Solid

Carebastine-d5 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Carebastine-d5 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 25)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50
Cato Research Chemicals Inc.	020-81960175	min.he@cato-chem.com	China	1958	55
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44843	58
Foshan Treasure Biotechnology Co., Ltd	0757-85921206 18520245316	2329783215@qq.com	China	12664	58
ChemeGen 中国	18818260767	sales@chemegen.com	China	6975	58
Shanghai Yiyan Biotechnology Co. , Ltd.	021-69985186 13611928337	3427709316@qq.com	China	7979	58
Shanghai isotope chemical co.,ltd	021-021-51600108 13062666369	sales@chinaisotope.com	China	4274	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11975	58
guoyungurui	18162595016	3287908757@qq.com	China	10338	58
Nanjing Shizhou Biology Technology Co.,Ltd	17301488900	judy.xia@synzest.com	China	12582	58

4-[4-[4-(Diphenylmethoxy-d5)-1-piperidinyl]-1-oxobutyl]-α,a-dimethylbenzeneacetic Acid
Carebastine-d5
4-[4-[4-(Diphenylmethoxy-d5)-1-piperidinyl]-1-oxobutyl]-a,a-dimethylbenzeneacetic Acid
4-[4-[4-(DiphenylMethoxy-d5)-1-piperidinyl]-1-oxobutyl]-α,α-diMethylbenzeneacetic Acid
Valine Impurity 136
1189661-02-6
C32H32D5NO4
Intermediates & Fine Chemicals
Isotope Labeled Compounds
Metabolites & Impurities
Pharmaceuticals
Isotope Labelled Compounds