Apricoxib

Apricoxib Struktur
197904-84-0
CAS-Nr.
197904-84-0
Englisch Name:
Apricoxib
Synonyma:
TG 01;CS 706;R 109339;Apricoxib;Benzenesulfonamide, 4-[2-(4-ethoxyphenyl)-4-methyl-1H-pyrrol-1-yl]-
CBNumber:
CB82627333
Summenformel:
C19H20N2O3S
Molgewicht:
356.44
MOL-Datei:
197904-84-0.mol

Apricoxib Eigenschaften

Schmelzpunkt:
148-151°C
Siedepunkt:
555.3±60.0 °C(Predicted)
Dichte
1.24±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
Löslichkeit
Chloroform (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
9.77±0.10(Predicted)
Farbe
Yellow

Sicherheit

Apricoxib Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Apricoxib, is an orally active, selective COX-2 inhibitor, used as as an analgesic and anti-inflammatory agent, and also has anticancer potential, since COX-2 inhibition can reduce tumor growth and augment therapy.

Enzyminhibitor

This oral COX-2 inhibitor (FW = 356.44 g/mol; CAS 162011-90-7), also named CS-706 and 4-[2- (4-ethoxyphenyl) -4-methyl-1H-pyrrol-1-yl]- benzene sulfonamide, targets Cyclooxygenase-2, which is over- expressed in advanced stage non-small-cell lung cancer (NSCLC), possibly as a result of elevated levels of COX-2-dependent prostaglandin E2 (PGE2). That said, a randomized, double-blind, placebo-controlled, multicenter phase II study found little evidence of efficacy of apricoxib in combination with either docetaxel or pemetrexed in patients with biomarker-selected NSCLC. See also Rofecoxib

Apricoxib Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Apricoxib Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 10)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
jkinfo@jkchemical.com China 96815 76
NCE Biomedical Co.,Ltd. 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
China 1494 55
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979
info@tsbiochem.com China 8072 58
SPIRO PHARMA
eric_feng1954@126.com China 9254 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226
sales@rrkchem.com China 56086 58
Energy Chemical 021-58432009 400-005-6266
marketing1@energy-chemical.com China 44843 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369
3477467573@qq.com China 8618 58
Suzhou Meishi Biotechnology Co., Ltd. 1173954148q
meishipharma@126.com China 20035 58

  • Apricoxib
  • CS 706
  • R 109339
  • TG 01
  • Benzenesulfonamide, 4-[2-(4-ethoxyphenyl)-4-methyl-1H-pyrrol-1-yl]-
  • 197904-84-0
  • Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
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