ChemicalBook >> CAS DataBase List >>4-Pyridinecarboxamide, 2-(cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-, hydrochloride (1:2)

4-Pyridinecarboxamide, 2-(cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-, hydrochloride (1:2)

4-Pyridinecarboxamide, 2-(cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-, hydrochloride (1:2) structure

CAS No.: 2320953-89-5

Chemical Name:: 4-Pyridinecarboxamide, 2-(cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-, hydrochloride (1:2)

Synonyms: 4-Pyridinecarboxamide, 2-(cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-, hydrochloride (1:2)

CBNumber:: CB010662764

Molecular Formula:: C22H29ClN4O2

Molecular Weight:: 416.95

MDL Number:

MOL File:: 2320953-89-5.mol

Last updated:2023-06-30 15:45:59

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4-Pyridinecarboxamide, 2-(cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-, hydrochloride (1:2) Properties

storage temp.	Desiccate at RT
solubility	Soluble to 100 mM in water and to 100 mM in DMSO
Water Solubility	water\|45.34\|100\|DMSO\|45.34\|100\|

4-Pyridinecarboxamide, 2-(cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-, hydrochloride (1:2) Chemical Properties,Uses,Production

Description

Potent and selective PRMT5 inhibitor (IC50 = 4 nM). Selective for PRMT5 over a panel of other PRMTs and lysine methyltransferases. Inhibits proliferation of mantle cell lymphoma (MCL) in vitro. To request the negative control for GSK 591, please fill out the SGC 2096 request form on the SGC website.

storage

Desiccate at RT

4-Pyridinecarboxamide, 2-(cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-, hydrochloride (1:2) Preparation Products And Raw materials

Raw materials

Preparation Products

4-Pyridinecarboxamide, 2-(cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-, hydrochloride (1:2) Suppliers

Global( 4)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Shanghai Rechem science Co., Ltd.	21-31433387 15618786686	sales@rechemscience.com	China	2991	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	+86-18521732826	market@aladdin-e.com	China	48465	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	28070	58

Supplier	Advantage
Aladdin Scientific	58
Shanghai Rechem science Co., Ltd.	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	58
TargetMol Chemicals Inc.	58

4-Pyridinecarboxamide, 2-(cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-, hydrochloride (1:2) 2320953-89-5