ChemicalBook >> CAS DataBase List >>3-Quinolinecarboxamide, 1,2-dihydro-N-(2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)-2-oxo-

3-Quinolinecarboxamide, 1,2-dihydro-N-(2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)-2-oxo-

3-Quinolinecarboxamide, 1,2-dihydro-N-(2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)-2-oxo- structure

CAS No.: 1246668-32-5

Chemical Name:: 3-Quinolinecarboxamide, 1,2-dihydro-N-(2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)-2-oxo-

Synonyms: PBS-1086;3-Quinolinecarboxamide, 1,2-dihydro-N-(2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)-2-oxo-

CBNumber:: CB010675036

Molecular Formula:: C16H12N2O5

Molecular Weight:: 312.28

MDL Number:

MOL File:: 1246668-32-5.mol

Last updated:2023-03-31 09:12:57

Request For Quotation

3-Quinolinecarboxamide, 1,2-dihydro-N-(2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)-2-oxo- Properties

Boiling point	755.7±60.0 °C(Predicted)
Density	1.59±0.1 g/cm3(Predicted)
pka	10.13±0.40(Predicted)

3-Quinolinecarboxamide, 1,2-dihydro-N-(2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)-2-oxo- Chemical Properties,Uses,Production

Description

PBS-1086 is a novel dual inhibitor of the canonical and noncanonical NF-κB pathways, increasing the magnitude and duration of initial EGFR inhibitor response in multiple NSCLC models, decreasing PDHK1 expression, and suppressing phosphorylation of the PDHK1 protein substrate PDHA1 in a panel of PTEN-deficient cell lines.

3-Quinolinecarboxamide, 1,2-dihydro-N-(2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)-2-oxo- Preparation Products And Raw materials

Raw materials

Preparation Products

3-Quinolinecarboxamide, 1,2-dihydro-N-(2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)-2-oxo- Suppliers

Global( 1)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	28091	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

3-Quinolinecarboxamide, 1,2-dihydro-N-(2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)-2-oxo- PBS-1086 1246668-32-5