ChemicalBook >> CAS DataBase List >>Boronophenylalanine B-10
Boronophenylalanine B-10
- CAS No.
- 80994-59-8
- Chemical Name:
- Boronophenylalanine B-10
- Synonyms
- Borofalan;Boronophenylalanine B-10;L-4-[10B]Boronophenylalanine;Borofalan (10B);L-4-Boronophenylalanine;Acetylcysteine Impurity 35;L-Phenylalanine,4-(borono-10B);10BenrichedL-4-boronophenylalanine;10BenrichedL-4-boronophenylalanine,GMPBPA;(S)-2-Amino-3-(4-(borono-10B)phenyl)propanoic acid
- CBNumber:
- CB01074488
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD02683190
- MOL File:
- Mol file
Last updated:2024-07-02 08:54:55
Melting point | 285-298 °C (decomp)(Solv: water (7732-18-5)) |
---|---|
storage temp. | Store at -20°C |
solubility | DMSO: Insoluble;Ethanol: Insoluble |
form | Solid |
color | White to off-white |
Water Solubility | Water: Insoluble |
FDA UNII | 963AI80S1B |
NCI Drug Dictionary | borofalan (10B) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H335-H319-H315 |
Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
Boronophenylalanine B-10 Chemical Properties,Uses,Production
Description
Boronophenylalanine B-10 is a boronophenylalanine and boron (boron-10) carrier for boron neutron capture therapy (BNCT) with potential anti-tumour activity. Upon administration, boron flange (10B) is mainly taken up by tumour cells. When irradiated with neutrons, boron flange (10B) absorbs neutrons and self-destructs, releasing short-range alpha radiation and "recoil" lithium in the tumour cells, leading to alpha radiation-induced tumour cell death. This highly selective local radio-targeting of tumour cells spares adjacent normal tissue.
Boronophenylalanine B-10 Preparation Products And Raw materials
Raw materials
Preparation Products
Boronophenylalanine B-10 Suppliers
Global( 50)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21667 | 55 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 13256 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25363 | 58 |
China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
Vicbio Biotechnology Co., Ltd. | 13691409741 | info@vicbio.com | China | 1719 | 58 |
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(S)-2-Amino-3-(4-(borono-10B)phenyl)propanoic acid
tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d
80994-59-8