ChemicalBook >> CAS DataBase List >>Boronophenylalanine B-10
Boronophenylalanine B-10
- CAS No.
- 80994-59-8
- Chemical Name:
- Boronophenylalanine B-10
- Synonyms
- Borofalan;Boronophenylalanine B-10;L-4-[10B]Boronophenylalanine;Borofalan (10B);L-4-Boronophenylalanine;Acetylcysteine Impurity 35;L-Phenylalanine,4-(borono-10B);10BenrichedL-4-boronophenylalanine;10BenrichedL-4-boronophenylalanine,GMPBPA;(S)-2-Amino-3-(4-(borono-10B)phenyl)propanoic acid
- CBNumber:
- CB01074488
- Molecular Formula:
- C9H12BNO4
- Molecular Weight:
- 208.21
- MDL Number:
- MFCD02683190
- MOL File:
- 80994-59-8.mol
Last updated:2024-11-19 23:02:33
| Melting point | 285-298 °C (decomp)(Solv: water (7732-18-5)) |
|---|---|
| Density | 1.347±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: Insoluble;Ethanol: Insoluble |
| form | Solid |
| color | White to off-white |
| Water Solubility | Water: Insoluble |
| FDA UNII | 963AI80S1B |
| NCI Drug Dictionary | borofalan (10B) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H319-H315 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
Boronophenylalanine B-10 Chemical Properties,Uses,Production
Description
Boronophenylalanine B-10 is a boronophenylalanine and boron (boron-10) carrier for boron neutron capture therapy (BNCT) with potential anti-tumour activity. Upon administration, boron flange (10B) is mainly taken up by tumour cells. When irradiated with neutrons, boron flange (10B) absorbs neutrons and self-destructs, releasing short-range alpha radiation and "recoil" lithium in the tumour cells, leading to alpha radiation-induced tumour cell death. This highly selective local radio-targeting of tumour cells spares adjacent normal tissue.
Boronophenylalanine B-10 Preparation Products And Raw materials
Raw materials
Preparation Products
Boronophenylalanine B-10 Suppliers
Global( 56)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 11849 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11922 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 |
| Vicbio Biotechnology Co., Ltd. | 13691409741 | info@vicbio.com | China | 1872 | 58 |
Related articles
- Borofalan (10B): Synthesis and Introduction
- Borofalan (10B) is synthesised using (S)-4-iodophenylalanine as raw material by chemical reaction.
- Dec 29，2023
View Lastest Price from Boronophenylalanine B-10 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Borofalan(10B)
80994-59-8
|
US $48.00-197.00 / mg | 99.75% | 10g | TargetMol Chemicals Inc. |
-
- Borofalan(10B)
80994-59-8
- US $48.00-197.00 / mg
- 99.75%
- TargetMol Chemicals Inc.
10BenrichedL-4-boronophenylalanine,GMPBPA
Borofalan (10B)
L-Phenylalanine,4-(borono-10B)
Acetylcysteine Impurity 35
L-4-Boronophenylalanine
L-4-[10B]Boronophenylalanine
Boronophenylalanine B-10
Borofalan
10BenrichedL-4-boronophenylalanine
4-Borono-L-phenylalanine 10B, BPA ( also provide BPA produced by GMP.)
Borofalan,BNCT,head and neck cancer,recurrent/locally advanced non-squamous cell carcinoma,Boron neutron capture therapy,Inhibitor,R/LA-nSCC,HNC,inhibit,recurrent squamous cell carcinoma,R-SCC
(S)-2-Amino-3-(4-(borono-10B)phenyl)propanoic acid
tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d
80994-59-8