ChemicalBook >> CAS DataBase List >>1H-Pyrrole-3-carboxamide, N-[(1S)-1-(methoxymethyl)-2-oxo-2-[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]ethyl]-1-(methylsulfonyl)-

1H-Pyrrole-3-carboxamide, N-[(1S)-1-(methoxymethyl)-2-oxo-2-[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]ethyl]-1-(methylsulfonyl)-

CAS No.
2468048-24-8
Chemical Name:
1H-Pyrrole-3-carboxamide, N-[(1S)-1-(methoxymethyl)-2-oxo-2-[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]ethyl]-1-(methylsulfonyl)-
Synonyms
FHT-1204;1H-Pyrrole-3-carboxamide, N-[(1S)-1-(methoxymethyl)-2-oxo-2-[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]ethyl]-1-(methylsulfonyl)-
CBNumber:
CB010892145
Molecular Formula:
C24H23N5O5S2
Molecular Weight:
525.6
MDL Number:
MOL File:
2468048-24-8.mol
Last updated:2024-07-02 08:54:55

1H-Pyrrole-3-carboxamide, N-[(1S)-1-(methoxymethyl)-2-oxo-2-[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]ethyl]-1-(methylsulfonyl)- Properties

Density 1.42±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
pka 7.32±0.50(Predicted)
form Solid
color Off-white to light brown

1H-Pyrrole-3-carboxamide, N-[(1S)-1-(methoxymethyl)-2-oxo-2-[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]ethyl]-1-(methylsulfonyl)- Chemical Properties,Uses,Production

Biological Activity

FHT-1204 is a potent SMARCA4/SMARCA2 ATPase (BRG1 and BRM) inhibitor with IC50s of ≤10 nM (WO2020160180A1; compound 70)[1].

References

[1]. Rishi G. Vaswani, et al. Compounds and uses thereof. WO2020160180A1.

1H-Pyrrole-3-carboxamide, N-[(1S)-1-(methoxymethyl)-2-oxo-2-[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]ethyl]-1-(methylsulfonyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Pyrrole-3-carboxamide, N-[(1S)-1-(methoxymethyl)-2-oxo-2-[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]ethyl]-1-(methylsulfonyl)- Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Shanghai XingMo Biotechnology Co., Ltd. 13524779951 2075692521@qq.com China 308 55
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11975 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19702 58
1H-Pyrrole-3-carboxamide, N-[(1S)-1-(methoxymethyl)-2-oxo-2-[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]ethyl]-1-(methylsulfonyl)- FHT-1204 2468048-24-8