9-Tetradecenoic acid, 1,1',1'',1'''-[(2R,14R)-5,8,11-trihydroxy-5,11-dioxido-4,6,10,12-tetraoxa-5,11-diophosphapentadecane-1,2,14,15-tetrayl] ester, sodium salt (1:2), (9Z,9'Z,9''Z,9'''Z)-
- CAS No.
- 2260669-33-6
- Chemical Name:
- 9-Tetradecenoic acid, 1,1',1'',1'''-[(2R,14R)-5,8,11-trihydroxy-5,11-dioxido-4,6,10,12-tetraoxa-5,11-diophosphapentadecane-1,2,14,15-tetrayl] ester, sodium salt (1:2), (9Z,9'Z,9''Z,9'''Z)-
- Synonyms
- Cardiolipin (14:1/14:1/14:1/14:1) (sodium salt);9-Tetradecenoic acid, 1,1',1'',1'''-[(2R,14R)-5,8,11-trihydroxy-5,11-dioxido-4,6,10,12-tetraoxa-5,11-diophosphapentadecane-1,2,14,15-tetrayl] ester, sodium salt (1:2), (9Z,9'Z,9''Z,9'''Z)-
- CBNumber:
- CB011018353
- Molecular Formula:
- C65H119NaO17P2
- Molecular Weight:
- 1257.59
- MDL Number:
- MOL File:
- 2260669-33-6.mol
9-Tetradecenoic acid, 1,1',1'',1'''-[(2R,14R)-5,8,11-trihydroxy-5,11-dioxido-4,6,10,12-tetraoxa-5,11-diophosphapentadecane-1,2,14,15-tetrayl] ester, sodium salt (1:2), (9Z,9'Z,9''Z,9'''Z)- Chemical Properties,Uses,Production
Uses
Glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states.
Biological Activity
Cardiolipin and cytochrome c interaction determines the function of proteins involved in oxidative phosphorylation and apoptosis. Cardiolipin involved in proton uptake pathway maintains the structure of enzymes participating. Cardiolipin controls the mitochondrial function and membrane potential. It offers structural support for the inner mitochondrial membrane and proteins in it. Altered cardiolipin concentration and composition have been implicated in pathological conditions including ischemia, hypothyroidism, aging, heart failure and cardioskeletal myopathy.', 'TMCL (1,1μ,2,2μ-tetramyristoyl cardiolipin) bilayers are useful in generating multilamellar vesicles. Defects in the metabolic pathway of cardiolipin is associated with Barth syndrome patients. Liposomes of TMCL with 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and cholesterol are potential drug-delivery systems. TMCL displays temperature dependant thermotropic phase transitions.
9-Tetradecenoic acid, 1,1',1'',1'''-[(2R,14R)-5,8,11-trihydroxy-5,11-dioxido-4,6,10,12-tetraoxa-5,11-diophosphapentadecane-1,2,14,15-tetrayl] ester, sodium salt (1:2), (9Z,9'Z,9''Z,9'''Z)- Preparation Products And Raw materials
Raw materials
Preparation Products
9-Tetradecenoic acid, 1,1',1'',1'''-[(2R,14R)-5,8,11-trihydroxy-5,11-dioxido-4,6,10,12-tetraoxa-5,11-diophosphapentadecane-1,2,14,15-tetrayl] ester, sodium salt (1:2), (9Z,9'Z,9''Z,9'''Z)- Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11974 | 58 |
SHANGHAI ZZBIO CO., LTD. | 15102117276 19921389125 | tech@zzbioco.com | China | 12065 | 58 |
Supplier | Advantage |
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Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
SHANGHAI ZZBIO CO., LTD. | 58 |