ChemicalBook >> CAS DataBase List >>6-ANILINO-5,8-QUINOLINEDIONE

6-ANILINO-5,8-QUINOLINEDIONE

6-ANILINO-5,8-QUINOLINEDIONE structure

CAS No.: 91300-60-6

Chemical Name:: 6-ANILINO-5,8-QUINOLINEDIONE

Synonyms: LY 83583;LY-83583 (LY83583);LY83583, 10 mM in DMSO;6-ANILINO-5,8-QUINOLINEDIONE;6-ANILINO-5,8-QUINOLINEQUINONE;6-(anilino)quinoline-5,8-dione;6-ANILINOQUINOLINE-5,8-QUINONE;6-(PHENYLAMINO)-5,8-QUINOLINEDIONE;6-(phenylamino)quinoline-5,8-dione;5,8-Quinolinedione, 6-(phenylamino)-

CBNumber:: CB0130280

Molecular Formula:: C15H10N2O2

Molecular Weight:: 250.25

MDL Number:: MFCD00210756

MOL File:: 91300-60-6.mol

Last updated:2025-01-27 09:38:02

Request For Quotation

6-ANILINO-5,8-QUINOLINEDIONE Properties

Melting point	184-185°C
Boiling point	446.9±45.0 °C(Predicted)
Density	1.400±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	0.1 M HCl: 1 mg/mL
form	solid
pka	-0.63±0.20(Predicted)
color	violet
CAS DataBase Reference	91300-60-6(CAS DataBase Reference)
FDA UNII	TD9FS56333
UNSPSC Code	41106305
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

Hazard Codes

Risk Statements

Safety Statements

WGK Germany

HS Code

2933499090

NFPA 704

	0
2		0

6-ANILINO-5,8-QUINOLINEDIONE price More Price(18)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	A6563	6-Anilinoquinoline-5,8-quinone ≥95% (TLC), solid	91300-60-6	5mg	$103.2	2024-03-01	Buy
Sigma-Aldrich	440205-M	LY 83583	91300-60-6	5mg-m	$101	2021-12-16	Buy
Sigma-Aldrich	440205-M	LY 83583 - CAS 91300-60-6 - Calbiochem A cell-permeable, competitive inhibitor of soluble guanylate cyclase (IC?? = 2 μM).	91300-60-6	5mg	$101	2021-12-16	Buy
Cayman Chemical	70230	LY 83583 ≥99%	91300-60-6	1mg	$18	2024-03-01	Buy
Cayman Chemical	70230	LY 83583 ≥99%	91300-60-6	5mg	$65	2024-03-01	Buy

Product number	Packaging	Price	Buy
A6563	5mg	$103.2	Buy
440205-M	5mg-m	$101	Buy
440205-M	5mg	$101	Buy
70230	1mg	$18	Buy
70230	5mg	$65	Buy

6-ANILINO-5,8-QUINOLINEDIONE Chemical Properties,Uses,Production

Chemical Properties

Red-Brown Solid

Uses

Inhibits nitric-oxide-induced activation of soluble guanylate cyclase (IC50=2μM) in a dose-dependent and reversible manner. It blocks acetylcholine induced vasorelaxation. Also an inhibitor of antigen-induced leukotriene release.

Uses

Inhibits nitric-oxide-induced activation of soluble guanylate cyclase (IC50=2) in a dose-dependent and reversible manner. It blocks acetylcholine induced vasorelaxation. Also an inhibitor of antigen-induced leukotriene release

Uses

LY83583 is an inhibitor of soluble guanylate cyclase and of cGMP production. It inhibits soluble guanylate cyclase in human platelets with an IC50 value of 2 μM. LY83583 also inhibits leukotriene synthesis in guinea pig lung and rat peritoneal cells with an IC50 value of 1.8 μM and is a noncompetitive inhibitor of glutathione reductase in bovine intestinal mucosa with a Ki value of 3 μM.[Cayman Chemical]

Definition

ChEBI: A quinolone that is quinoline-5,8-dione in which the hydrogen at position 6 is replaced by an anilino group.

Biological Activity

Primary Target
soluble guanylate cyclase', 'Target IC50: 2 μM against soluble guanylate cyclase

6-ANILINO-5,8-QUINOLINEDIONE synthesis

Synthesis of 6-ANILINO-5,8-QUINOLINEDIONE from 5-Amino-8-hydroxyquinoline

6-ANILINO-5,8-QUINOLINEDIONE Preparation Products And Raw materials

Raw materials

Preparation Products

6-ANILINO-5,8-QUINOLINEDIONE Suppliers

Global( 93)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9639	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	China	52849	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43340	58
Hebei Weibang Biotechnology Co., Ltd	+8615350571055	Sibel@weibangbio.com	China	6087	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58
Mainchem Co., Ltd.	+86-0592-6210733	sale@mainchem.com	China	32343	55
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15839	69
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32321	50

Supplier	Advantage
TargetMol Chemicals Inc.	58
Finetech Industry Limited	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
LEAPCHEM CO., LTD.	58
Hebei Weibang Biotechnology Co., Ltd	58
Amadis Chemical Company Limited	58
Mainchem Co., Ltd.	55
J & K SCIENTIFIC LTD.	76
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Chemsky（shanghai）International Co.,Ltd.	50

View Lastest Price from 6-ANILINO-5,8-QUINOLINEDIONE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-19	LY83583 91300-60-6	US $55.00-178.00 / mg		98.71%	10g	TargetMol Chemicals Inc.
	2021-08-11	6-ANILINO-5,8-QUINOLINEDIONE 91300-60-6	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

LY83583
91300-60-6
US $55.00-178.00 / mg
98.71%
TargetMol Chemicals Inc.

6-ANILINO-5,8-QUINOLINEDIONE
91300-60-6
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

91300-60-6(6-ANILINO-5,8-QUINOLINEDIONE)Related Search:

4'-Hydroxyacetophenone BAY 41-2272 GUANYLIN (HUMAN) ODQ TYRPHOSTIN AG 1288

YC-1 GUANYLIN (RAT) Protoporphyrin IX L-Carnosine NS-2028

6-ANILINO-5,8-QUINOLINEDIONE 1-PHENYL-N-(PYRIDIN-3-YLMETHYL)METHYLAMINE 3-Pyridineethaneamine (2-PYRIDIN-3-YLETHYL)METHYLAMINE Ethanone, 1-(3-methyl-2-pyridinyl)- (9CI)

3-(2-PYRIDYL)-1-PROPENE 5,8-QUINOLINEQUINONE

1of4

6-ANILINOQUINOLINE-5,8-QUINONE 6-(Phenylamino)-5,8-quinolinedione, LY-83,583 6-(anilino)quinoline-5,8-dione 6-(phenylamino)quinoline-5,8-dione 5,8-Dihydro-5,8-dioxo-6-(phenylaMino)quinoline 5,8-Dihydro-5,8-dioxo-6-(phenylamino)quinoline, [(5,8-Dihydro-5,8-dioxoquinolin-6-yl)amino]benzene, 6-Anilinoquinoline-5,8-dione LY 83583 6-(PHENYLAMINO)-5,8-QUINOLINEDIONE 6-ANILINO-5,8-QUINOLINEDIONE 6-ANILINO-5,8-QUINOLINEQUINONE LY 83583 - CAS 91300-60-6 - Calbiochem (4-methyl-2-oxo-1-benzopyran-7-yl)oxy-phenylphosphinic acid LY-83583 (LY83583) 5,8-Quinolinedione, 6-(phenylamino)- LY83583, Soluble guanylate cyclase inhibitor LY83583, 10 mM in DMSO 91300-60-6 Cell Biology Cell Signaling and Neuroscience BioChemical Cyclic Nucleotide Metabolism Guanylyl Cyclase Inhibitors G Proteins and Cyclic Nucleotides All Inhibitors Inhibitors Nitric Oxide Reagents Aromatics Heterocycles