ChemicalBook >> CAS DataBase List >>N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE

N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE

N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE structure

CAS No.: 182073-77-4

Chemical Name:: N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE

Synonyms: ZD8321;ZD-8321,ZD8321;N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE;L-Prolinamide, N-(methoxycarbonyl)-L-valyl-N-[(1S)-3,3,3-trifluoro-1-(1-methylethyl)-2-oxopropyl]-

CBNumber:: CB01476918

Molecular Formula:: C18H28F3N3O5

Molecular Weight:: 423.43

MDL Number:: MFCD00949903

MOL File:: 182073-77-4.mol

Last updated:2024-07-02 08:54:57

Request For Quotation

N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE Properties

Boiling point	573.9±50.0 °C(Predicted)
Density	1.232±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
form	Solid
pka	11.22±0.46(Predicted)
color	Light yellow to yellow
FDA UNII	T7FIA2S66D

N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	KIN0001252	ZD-8321 95.00%	182073-77-4	5MG	$503.07	2021-12-16	Buy

Product number	Packaging	Price	Buy
KIN0001252	5MG	$503.07	Buy

N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE Chemical Properties,Uses,Production

Biological Activity

ZD8321 is a potent inhibitor of human Neutrophil elastase (NE) with a Ki value of 13±1.7 nM.

in vitro

TNFα-activated HUVEC is dose dependently inhibited by ZD8321.The adhesion between cancer cells with high elastase activity and TNFα-activated HUVEC is also inhibited by ZD8321.

target

Ki: 13±1.7 nM (Neutrophil elastase)

N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE Suppliers

Global( 8)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
MedChemexpress LLC	021-58955995	sales@medchemexpress.cn	United States	4863	58
Sichuan Wei Keqi Biological Technology Co., Ltd.	028-81700200 18116577057	3003855609@qq.com	China	7887	56
BOC Sciences	--	info@bocsci.com	USA	0	65
Jinan ponder chemical co. LTD	0531-0000	thinklifescience@163.com	China	19690	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840 15801484223;	psaitong@jm-bio.com	China	29778	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	23963	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
MedChemexpress LLC	58
Sichuan Wei Keqi Biological Technology Co., Ltd.	56
BOC Sciences	65
Jinan ponder chemical co. LTD	58
Beijing Jin Ming Biotechnology Co., Ltd.	58
TargetMol Chemicals Inc.	58

N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE ZD8321 L-Prolinamide, N-(methoxycarbonyl)-L-valyl-N-[(1S)-3,3,3-trifluoro-1-(1-methylethyl)-2-oxopropyl]- ZD-8321,ZD8321 182073-77-4 C18H28F3N3O5