Vincine

CAS No.
4752-37-8
Chemical Name:
Vincine
Synonyms
Vincine;Vincamine Impurity 26;(3α,16α)-14,15-Dihydro-14β-hydroxy-11-methoxyeburnamenine-14α-carboxylic acid methyl ester;1H-Indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylic acid, 13a-ethyl-2,3,5,6,12,13,13a,13b-octahydro-12-hydroxy-9-methoxy-, methyl ester, (12S,13aS,13bS)-
CBNumber:
CB01485479
Molecular Formula:
C22H28N2O4
Molecular Weight:
384.46872
MDL Number:
MOL File:
4752-37-8.mol
Last updated:2023-07-14 17:48:43

Vincine Properties

Melting point 212-4°C
Boiling point 538.4±50.0 °C(Predicted)
Density 1.36±0.1 g/cm3(Predicted)
pka 12.00±0.40(Predicted)

Vincine Chemical Properties,Uses,Production

Description

One of a number of alkaloids isolated from Vinca erecta RgL et Schmalh, this base crystallizes as colourless needles from MeOH. It has a specific rotation of [α]D + 36° (pyridine).

References

Plat et aI., Bull Soc. Chim. Fr., 1082 (1962) Strouf, Trojanek, Chem & Ind., 48, 2037 (1962) Kuchenkova, Yuldashev, Yunusov, DokZ. Akad. Nauk. Uzbek SSR, 11,42 (1964) Malikov, Kas'mov, Yunusov, Khim. Prir. Soedin., 6 (1970)

Vincine Preparation Products And Raw materials

Raw materials

Preparation Products

(3α,16α)-14,15-Dihydro-14β-hydroxy-11-methoxyeburnamenine-14α-carboxylic acid methyl ester Vincine 1H-Indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylic acid, 13a-ethyl-2,3,5,6,12,13,13a,13b-octahydro-12-hydroxy-9-methoxy-, methyl ester, (12S,13aS,13bS)- Vincamine Impurity 26 4752-37-8