ChemicalBook >> CAS DataBase List >>2-Pyridinecarboxaldehyde
2-Pyridinecarboxaldehyde
- CAS No.
- 1121-60-4
- Chemical Name:
- 2-Pyridinecarboxaldehyde
- Synonyms
- PICOLINALDEHYDE;PYRIDINE-2-ALDEHYDE;PYRIDINE-2-CARBOXALDEHYDE;PYRIDINE-2-CARBALDEHYDE;2-Pyridinecarboxyaldehyde;2-FORMYLPYRIDINE;2-PYRIDINECARBALDEHYDE;Pyridine-2-formaldehyde;2-PA;Picolinal
- CBNumber:
- CB0153722
- Molecular Formula:
- C6H5NO
- Molecular Weight:
- 107.11
- MDL Number:
- MFCD00006290
- MOL File:
- 1121-60-4.mol
- MSDS File:
- SDS
Last updated:2025-01-27 09:38:02
| Melting point | -21--22°C |
|---|---|
| Boiling point | 181 °C(lit.) |
| Density | 1.126 g/mL at 25 °C(lit.) |
| vapor pressure | 73Pa at 20℃ |
| refractive index |
n |
| Flash point | 130 °F |
| storage temp. | 2-8°C |
| form | liquid (strong colored) |
| pka | 3.8(at 20℃) |
| color | Clear yellow to yellow-brown |
| PH | 6.5 (111g/l, H2O, 20℃) |
| Water Solubility | miscible |
| Sensitive | Air Sensitive |
| BRN | 105341 |
| InChIKey | CSDSSGBPEUDDEE-UHFFFAOYSA-N |
| LogP | 0.714 at 20.5℃ |
| CAS DataBase Reference | 1121-60-4(CAS DataBase Reference) |
| FDA UNII | KH86K8FHZ2 |
| NIST Chemistry Reference | 2-Pyridinecarboxaldehyde(1121-60-4) |
| EPA Substance Registry System | 2-Pyridinecarboxaldehyde (1121-60-4) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H317-H318-H330-H335 | |||||||||
| Precautionary statements | P260-P280-P301+P312-P302+P352-P304+P340+P310-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,Xi,N,T,F | |||||||||
| Risk Statements | 10-22-36/37/38-51/53-46-43-34-23-52 | |||||||||
| Safety Statements | 7-26-36-61-53-45-36/37/39-29-16-36/37 | |||||||||
| RIDADR | UN 1989 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 8-10-23 | |||||||||
| Hazard Note | Irritant/Keep Cold/Air Sensitive | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29333999 | |||||||||
| NFPA 704 |
|
2-Pyridinecarboxaldehyde price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P62003 | 2-Pyridinecarboxaldehyde 99% | 1121-60-4 | 25g | $38.8 | 2024-03-01 | Buy |
| Sigma-Aldrich | P62003 | 2-Pyridinecarboxaldehyde 99% | 1121-60-4 | 100g | $82 | 2024-03-01 | Buy |
| TCI Chemical | P0425 | 2-Pyridinecarboxaldehyde >98.0%(GC) | 1121-60-4 | 25g | $68 | 2024-03-01 | Buy |
| TCI Chemical | P0425 | 2-Pyridinecarboxaldehyde >98.0%(GC) | 1121-60-4 | 100g | $166 | 2024-03-01 | Buy |
| Alfa Aesar | A11391 | Pyridine-2-carboxaldehyde, 99% | 1121-60-4 | 25g | $38.6 | 2024-03-01 | Buy |
2-Pyridinecarboxaldehyde Chemical Properties,Uses,Production
Chemical Properties
Yellow liquid
Uses
2-Pyridinecarboxaldehyde has been used:
- To synthesize chitosan based bifunctionalized adsorbent.
- In the aldol addition reaction with pyruvate in the presence of 2-keto-3-deoxy-6-phosphogluconate aldolase (KDPG) catalyst to form (S)-4-hydroxy-2-keto-4-(2′-pyridyl)butyrate.
- In the condensation reaction with (S)-(?)-α-methylbenzylamine and (R)-(+)-α-methylbenzylamine to synthesize two chiral (S)-(?)- and (R)-(+)Schiff base compounds.
It can also be combined with thiosemicarbazide to form 2-pyridinecarboxaldehyde thiosemicarbazone ligand (L) which can further complex with Ni(II) and Cu(II) salts (MX) to form [M(L)2X2] complexes.
Definition
ChEBI: 2-Pyridinecarboxaldehyde is a pyridinecarbaldehyde that is pyridine in which the hydrogen at position 2 is replaced by a formyl group.
Synthesis Reference(s)
Synthetic Communications, 23, p. 1775, 1993 DOI: 10.1080/00397919308011276
Purification Methods
Purification is achieved by bubbling sulfur dioxide into a solution of 50g of the aldehyde in 250mL of boiled water, under nitrogen, at 0o, until precipitation is complete. The bisulfite addition compound is filtered off rapidly and, after washing with a little water, is refluxed in 17% HCl (200mL) under nitrogen until a clear solution is obtained. Neutralisation with NaHCO3 and extraction with ether separated the aldehyde which is recovered by drying the extract, then distilling twice, under nitrogen. [Kyte et al. J Chem Soc 4454 1960, Beilstein 21 I 287, 21 III/IV 3495, 21/7 V 293.]
2-Pyridinecarboxaldehyde Preparation Products And Raw materials
Raw materials
1of4
Preparation Products
Global( 645)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Anhui Dexinjia Biopharm Co., Ltd | +86-531-82371986 +86-15064117275 | sales01@jndxj.com | China | 290 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531157085 | abby@chuanghaibio.com | China | 8808 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5868 | 58 |
| Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-18712993135 | sales01@tairunfaz.com | China | 8051 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18137 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Anhui Zhongda Biotechnology Co., Ltd | +8619956560829 | justine@zhongda-biotech.com | China | 286 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20235 | 58 |
| HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +8615350851019 | admin@86-ss.com | China | 1001 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
Related articles
- Study on chemical properties, synthesis, and application of 2-pyridinecarboxaldehyde
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- Sep 4，2024
View Lastest Price from 2-Pyridinecarboxaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-24 | 2-Pyridinecarboxaldehyde
1121-60-4
|
US $6.00 / kg | 1kg | 0.99 | 100000 | Hebei Fengjia New Material Co., Ltd | |
 |
2025-04-23 | 2-Pyridinecarboxaldehyde
1121-60-4
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-04-23 | 2-Pyridinecarboxaldehyde
1121-60-4
|
US $100.00-75.00 / kg | 1kg | 99% | 5000Ton | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD |
-
- 2-Pyridinecarboxaldehyde
1121-60-4
- US $6.00 / kg
- 0.99
- Hebei Fengjia New Material Co., Ltd
-
- 2-Pyridinecarboxaldehyde
1121-60-4
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 2-Pyridinecarboxaldehyde
1121-60-4
- US $100.00-75.00 / kg
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
1121-60-4(2-Pyridinecarboxaldehyde)Related Search:
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2-FORMYLPYRIDINE
2-PYRIDINECARBALDEHYDE
PYRIDINE-2-CARBOXALDEHYDE
PYRIDINE-2-ALDEHYDE
PYRIDINE-2-CARBALDEHYDE
PICOLINALDEHYDE
2-Pyridinecarboxyaldehyde
Pyridine-2-formaldehyde
2-Pyridinecarboxaldehyde (9CI, ACI)
Picosulfate Impurity 20
Pyridine 2 - aldehyde ( under
development )
Sodium Picosulfate Impurity 11
2-Pyridine carboxaldehyde or (pyridine-2-aldehyde)
Nicotinamide Impurity 167 Monomer
1121-60-4
Pyridines
Building Blocks
Heterocyclic Building Blocks
C6