Anethole trithione
- CAS No.
- 532-11-6
- Chemical Name:
- Anethole trithione
- Synonyms
- Sulfarlem;AnetholTrithione;Trithio;Heporal;Mucinol;skf1717;Sulfogal;Felviten;SKF 1717;Sufralem
- CBNumber:
- CB0168937
- Molecular Formula:
- C10H8OS3
- Molecular Weight:
- 240.36
- MDL Number:
- MFCD00129751
- MOL File:
- 532-11-6.mol
- MSDS File:
- SDS
| Melting point | 111° |
|---|---|
| Boiling point | 353.09°C (rough estimate) |
| Density | 1.4406 (rough estimate) |
| refractive index | 1.5080 (estimate) |
| storage temp. | 2-8°C |
| solubility | Chloroform[soluble in] |
| solubility | soluble in Chloroform |
| form | powder to crystal |
| color | Orange-colored prisms from butyl acetate |
| Odor | very bitter taste |
| InChI | InChI=1S/C10H8OS3/c1-11-8-4-2-7(3-5-8)9-6-10(12)14-13-9/h2-6H,1H3 |
| InChIKey | KYLIZBIRMBGUOP-UHFFFAOYSA-N |
| SMILES | S1C(C2=CC=C(OC)C=C2)=CC(=S)S1 |
| CAS DataBase Reference | 532-11-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| NCI Dictionary of Cancer Terms | anetholtrithione |
| FDA UNII | QUY32964DJ |
| NIST Chemistry Reference | 3H-1,2-Dithiole-3-thione, 5-(4-methoxyphenyl)-(532-11-6) |
| ATC code | A16AX02 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H332-H335 | |||||||||
| Precautionary statements | P261-P280-P305+P351+P338 | |||||||||
| HS Code | 2934.99.3000 | |||||||||
| Toxicity | LD50 orl-mus: 3850 mg/kg NIIRDN 6,25,82 | |||||||||
| NFPA 704 |
|
Anethole trithione price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | A3364 | Anethole Trithione | 532-11-6 | 5G | $70 | 2024-03-01 | Buy |
| TCI Chemical | A3364 | Anethole Trithione | 532-11-6 | 25G | $278 | 2024-03-01 | Buy |
| Biosynth Carbosynth | FA41106 | Anethole trithione | 532-11-6 | 500mg | $90 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA41106 | Anethole trithione | 532-11-6 | 5G | $375 | 2021-12-16 | Buy |
| Matrix Scientific | 074707 | Anethole trithione 95+% | 532-11-6 | 5g | $599 | 2021-12-16 | Buy |
Anethole trithione Chemical Properties,Uses,Production
Description
Anise trisulfide, also known as bile vita, is a secretory choleretic drug, which can significantly enhance liver glutathione levels, significantly enhance glutamyl cysteine synthase, glutathione reductase and glutathione sulfur Transferase activity, reduce glutathione peroxidase activity, enhance liver cell viability, and increase bile secretion. Without increasing the burden on the liver, it can reduce liver portal pressure, eliminate liver congestion and other symptoms of hepatitis lesions, promote liver cell activation, and contribute to the improvement and recovery of liver function.
Originator
Sialor,Paladin Labs
Uses
Anethole trithione is a choleretic drug that can be effective in the treatment of dry mouth, including drug-induced xerostomia. Research suggests that Anethole trithione may exert its therapeutic effects by acting on the alpha-CGRP nerves in the salivary glands, which in turn promotes salivary secretion[1-2].
Definition
ChEBI: Anetholtrithion is a member of methoxybenzenes.
Manufacturing Process
1 mol anethol (1-methoxy-4-propenyl-benzene) and 3 mol sulfur were heated in an open vessel to temperature 190°-200°C. H2S was removed at this temperature. On cooling the reaction mixture was getting solid. The solid product was recrystallizated from acetone or ethanol to give the orange-red needles of 5-(4-methoxyphenyl)-3H-1,2-dithiole-3-thione; MP 108.5°C.
Therapeutic Function
Salivation stimulant, Choleretic, Neuroprotective
Safety Profile
Poison by intramuscular route.Moderately toxic by ingestion and intraperitoneal routes.Experimental reproductive effects. When heated todecomposition it emits toxic fumes of SOx.
References
[1] TOSHIAKI NAGANO; Masaharu T. Enhancement of salivary secretion and neuropeptide (substance P, α-calcitonin gene-related peptide) levels in saliva by chronic anethole trithione treatment[J]. Journal of Pharmacy and Pharmacology, 2010. DOI:10.1211/0022357011778098.
[2] GLENERT U. Effects of chronic anethole trithione and amitriptyline treatment on rat parotid gland signalling[J]. European Journal of Pharmacology: Molecular Pharmacology, 1992. DOI:10.1016/0922-4106(92)90081-6.
Anethole trithione Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| HUBEI VITORCOME PHARMACEUTICAL CO.,LTD | +8615629646827 | hgsk@saikangpharm.com | China | 8 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8617732866630 | abby@chuanghaibio.com | China | 8773 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86-13288715578 | sales@hbmojin.com | China | 12749 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29731 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21622 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6369 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from Anethole trithione manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-07-09 | Anethol Trithione
532-11-6
|
US $0.00 / Kg/Bag | 2Kg/Bag | 0.99 | 20 tons | Sinoway Industrial co., ltd. | |
 |
2025-07-07 | Anethole trithione
532-11-6
|
US $40.00 / KG | 1KG | 99% | 20tons | Hebei Mujin Biotechnology Co.,Ltd | |
 |
2025-06-24 | Anethole trithione
532-11-6
|
US $10.00 / KG | 100KG | 99% | 100 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Anethol Trithione
532-11-6
- US $0.00 / Kg/Bag
- 0.99
- Sinoway Industrial co., ltd.
-
- Anethole trithione
532-11-6
- US $40.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- Anethole trithione
532-11-6
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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