Methyl 3-amino-4-methylthiophene-2-carboxylate
- CAS No.
- 85006-31-1
- Chemical Name:
- Methyl 3-amino-4-methylthiophene-2-carboxylate
- Synonyms
- 3-AMINO-4-METHYL-2-THIOPHENECARBOXYLIC ACID METHYL ESTER;3-Amino Articaine;3-AMINO-4-METHYLTHIOPHENECARBOXYLIC ACID METHYL ESTER;M3A4MT2C;Articaine-002;Articaine Impurity I;Articaine Impurity 9;LABOTEST-BB LT00453517;Articaine EP Impurity I;Articaine intermediate E
- CBNumber:
- CB0189112
- Molecular Formula:
- C7H9NO2S
- Molecular Weight:
- 171.22
- MDL Number:
- MFCD00051822
- MOL File:
- 85006-31-1.mol
- MSDS File:
- SDS
Melting point | 85-88 °C (lit.) |
---|---|
Boiling point | 318.6±37.0 °C(Predicted) |
Density | 1.264±0.06 g/cm3(Predicted) |
Flash point | >100°C |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | Chloroform (Slightly), Methanol (Slightly) |
pka | 1.71±0.10(Predicted) |
form | Solid |
color | Pale Yellow |
Water Solubility | 1g/L at 35℃ |
BRN | 973196 |
InChIKey | YICRPERKKBDRSP-UHFFFAOYSA-N |
LogP | 1.28 |
CAS DataBase Reference | 85006-31-1(CAS DataBase Reference) |
FDA UNII | 3LA24473AS |
NIST Chemistry Reference | Methyl 3-amino-4-methylthiophene-2-carboxylate(85006-31-1) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36-24/25-22 | |||||||||
WGK Germany | 2 | |||||||||
Hazard Note | Irritant | |||||||||
HS Code | 29349990 | |||||||||
NFPA 704 |
|
Methyl 3-amino-4-methylthiophene-2-carboxylate price More Price(44)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 546658 | Methyl 3-amino-4-methylthiophene-2-carboxylate 97% | 85006-31-1 | 5g | $33.2 | 2024-03-01 | Buy |
Sigma-Aldrich | 546658 | Methyl 3-amino-4-methylthiophene-2-carboxylate 97% | 85006-31-1 | 25g | $127 | 2024-03-01 | Buy |
TCI Chemical | M1772 | Methyl 3-Amino-4-methylthiophene-2-carboxylate >98.0%(GC) | 85006-31-1 | 5g | $29 | 2024-03-01 | Buy |
TCI Chemical | M1772 | Methyl 3-Amino-4-methylthiophene-2-carboxylate >98.0%(GC) | 85006-31-1 | 25g | $101 | 2024-03-01 | Buy |
Alfa Aesar | A10115 | Methyl 3-amino-4-methylthiophene-2-carboxylate, 98% | 85006-31-1 | 5g | $59.2 | 2021-12-16 | Buy |
Methyl 3-amino-4-methylthiophene-2-carboxylate Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powder
Uses
Methyl 3-Amino-4-methylthiophene-2-carboxylate is a versatile reactant used in various syntheses. It is used in the preparation of (oxalylamino)benzoic acids and (carboxyheteroarylamino)oxalic acids as selective and orally bioavailable nonpeptide inhibitors of protein-tyrosine phosphatase 1B.
Application
methyl 3-amino-4-methylthiophene-2-carboxylate is the starting material used in the synthesis of the local anesthetic articaine.
7-Methylthieno[3,2-d]pyrimidin-4(3H)-one was prepared using methyl 3-amino-4-methylthiophene-2-carboxylate.
The reaction of 4-bromotoluene (0.171 g, 1 mmol), methyl 3-amino-4-methylthiophene-2-carboxylate(0.342 g, 2 mmol) and KOAc (0.196 g, 2 mmol) in the presence of PdCl(C3H5)(dppb) (12.2 mg, 0.02mmol) in DMAc at 120 °C affords the corresponding Methyl 3-amino-4-methyl-5-p-tolylthiophene-2-carboxylate in 81% (0.212 g) isolated yield.
Definition
ChEBI: Methyl 3-amino-4-methylthiophene-2-carboxylate is a thiophenecarboxylic acid.
![2689-70-5](/CAS/GIF/2689-70-5.gif)
![85006-31-1](/CAS/GIF/85006-31-1.gif)
Methyl 3-amino-4-methylthiophene-2-carboxylate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of2
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12450 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | xinshengkeji@xsmaterial.com | China | 1090 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 16914 | 58 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 811 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9332 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
View Lastest Price from Methyl 3-amino-4-methylthiophene-2-carboxylate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
![]() |
2024-08-22 | Methyl 3-amino-4-methylthiophene-2-carboxylate
85006-31-1
|
US $0.00 / Kg/Drum | 1KG | 99%min HPLC | 1000kgs | WUHAN FORTUNA CHEMICAL CO., LTD | |
![]() |
2024-08-17 | Methyl 3-amino-4-methylthiophene-2-carboxylate
85006-31-1
|
US $5.00 / kg | 1kg | 0.99 | 10000 | Hebei Fengjia New Material Co., Ltd | |
![]() |
2023-10-17 | Methyl 3-amino-4-methylthiophene-2-carboxylate
85006-31-1
|
US $35.00-25.00 / kg | 1kg | 99% | 20 Ton | Hebei Xinsheng New Material Technology Co., LTD. |
-
- Methyl 3-amino-4-methylthiophene-2-carboxylate
85006-31-1
- US $0.00 / Kg/Drum
- 99%min HPLC
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Methyl 3-amino-4-methylthiophene-2-carboxylate
85006-31-1
- US $5.00 / kg
- 0.99
- Hebei Fengjia New Material Co., Ltd
-
- Methyl 3-amino-4-methylthiophene-2-carboxylate
85006-31-1
- US $35.00-25.00 / kg
- 99%
- Hebei Xinsheng New Material Technology Co., LTD.