ANTI-HOGG1
- CAS No.
- Chemical Name:
- ANTI-HOGG1
- Synonyms
- Anti-Mmh;Anti-MUTM;Anti-HMMH;Anti-OGH1;ANTI-HOGG1;ANTI-OGG1 (HUMAN);Anti-8-oxoguanine DNA glycosylase;Anti-OGG1 antibody produced in goat;Anti-OGG1 antibody produced in mouse;Anti-OGG1 antibody produced in rabbit
- CBNumber:
- CB0193461
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD02685916
- MOL File:
- Mol file
ANTI-HOGG1 price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB5701578 | Anti-OGG1 antibody produced in rabbit | 100UL | $389 | 2023-06-20 | Buy | |
| Sigma-Aldrich | SAB1400189 | Anti-OGG1 antibody produced in mouse IgG fraction of antiserum, buffered aqueous solution | 50μG | $503 | 2023-01-07 | Buy |
ANTI-HOGG1 Chemical Properties,Uses,Production
General Description
This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. (provided by RefSeq)
Biochem/physiol Actions
The gene OGG1 (8-oxoguanine DNA glycosylase) is responsible for the excision of 8-oxoguanine, which is the most common form of oxidative DNA damage and is removed by the base excision repair pathway. OGG1 also has lyase activity that results in a single strand break. Variation in OGG1 (8-oxoguanine DNA glycosylase) is associated with age-related cataract and serves as a genetic biomarker in indicating the same.
ANTI-HOGG1 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-HOGG1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Riedel-de Haen AG | -- | United States | 6773 | 87 | |
| Fluorochem Ltd | -- | vernam@fluorochem.co.uk | United Kingdom | 6375 | 65 |
| Alexis Corporation | -- | alexis-ch@alexis-corp.ch | Switzerland | 3599 | 74 |
| A.G. Scientific, Inc. | -- | support@agscientific.com | United States | 1066 | 71 |
| Novus Biologicals, Inc. | -- | novus@novusbio.com | United States | 175 | 77 |
| Fluorochem Ltd. | -- | enquiries@fluorochem.co.uk | United Kingdom | 6401 | 74 |
| BIOTREND Chemikalien GmbH | -- | jaeger@biotrend.com | Germany | 6115 | 76 |
| Supplier | Advantage |
|---|---|
| Riedel-de Haen AG | 87 |
| Fluorochem Ltd | 65 |
| Alexis Corporation | 74 |
| A.G. Scientific, Inc. | 71 |
| Novus Biologicals, Inc. | 77 |
| Fluorochem Ltd. | 74 |
| BIOTREND Chemikalien GmbH | 76 |