ChemicalBook >> CAS DataBase List >>Thiosildenafil
Thiosildenafil
- CAS No.
- 479073-79-5
- Chemical Name:
- Thiosildenafil
- Synonyms
- xidi;Sildenafil N;Thiosildenafil;Sildenafil Impurity N;Pinacolborane Impurity 5;Thiosildenafil in Methanol;Demethyltadalafil Solution, 100ppm;ethyl4-amino-1-methyl-3-propyl-1H-pyrazole-5-carboxylate;5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidine-7-thione;5-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidine-7(6H)-thione
- CBNumber:
- CB02104269
- Molecular Formula:
- C22H30N6O3S2
- Molecular Weight:
- 490.64
- MDL Number:
- MFCD11977921
- MOL File:
- 479073-79-5.mol
Last updated:2023-06-08 09:03:09
| Melting point | 172-174?C |
|---|---|
| Boiling point | 676.1±65.0 °C(Predicted) |
| Density | 1.39±0.1 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Heated) |
| form | Solid |
| pka | 5.97±0.42(Predicted) |
| color | Pale Yellow to Light Yellow |
| FDA UNII | HRL3FWK7XV |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
Thiosildenafil price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 13939 | Thiosildenafil ≥98% | 479073-79-5 | 1mg | $43 | 2024-03-01 | Buy |
| Cayman Chemical | 13939 | Thiosildenafil ≥98% | 479073-79-5 | 5mg | $187 | 2024-03-01 | Buy |
| Cayman Chemical | 13939 | Thiosildenafil ≥98% | 479073-79-5 | 10mg | $290 | 2024-03-01 | Buy |
| Usbiological | 021790 | Thiosildenafil | 479073-79-5 | 10mg | $460 | 2021-12-16 | Buy |
| TRC | T371500 | Thiosildenafil | 479073-79-5 | 10mg | $185 | 2021-12-16 | Buy |
Thiosildenafil Chemical Properties,Uses,Production
Description
Thiosildenafil is a derivative of the phosphodiesterase 5 (PDE5) inhibitor sildenafil .
Chemical Properties
Pale Yellow Solid
Uses
An analog of labelled Sildenafil; a novel pyrazolopyrimidinethiones as PDE5 inhibitor.
Uses
An analog of Sildenafil; a novel pyrazolopyrimidinethiones as PDE5 inhibitor.
Uses
Sildenafil, marketed under the trade name Viagra?, is a potent cGMP-specific phosphodiesterase inhibitor that is highly selective for PDE5. While most notable for its use in the treatment of erectile dysfunction, sildenafil’s vasorelaxant properties have also been used to control vascular tone in pulmonary arterial hypertension and high-altitude pulmonary edema associated with altitude sickness. Thiosildenafil is a derivative of sildenafil that has been found as an adulterant in dietary supplements advertising sexual enhancement for men. The biological characteristics of thiosildenadil have not been reported.[Cayman Chemical]
Synthesis of Thiosildenafil from 5-(2-ETHOXYPHENYL)-1-METHYL-3-N-PROPYL-1,6-DIHYDRO-7H-PYRAZOLO[4,3-D]-7-PYRIMIDINONE
Thiosildenafil Preparation Products And Raw materials
Global( 47)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 |
| JIUWEI | 13323819089 | 565251196@qq.com | China | 7 | 58 |
| Henan Wasai Biological Technology Co. LTD | 13526611694 | 2582571190@qq.com | China | 69 | 58 |
| Shandong longtai fine chemical co., ltd | 15169750147 | 1908452573@qq.com | China | 49 | 58 |
| Shandong Wankang Biotechnology Co. , Ltd. | 131-7317-1119 13173171119 | 918582503@qq.com | China | 25 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94657 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14055 | 65 |
479073-79-5(Thiosildenafil)Related Search:
Sildenafil EP IMpurity D
Propoxyphenyl Sildenafil
DESMETHYL SILDENAFIL
Homo Sildenafil
Sildenafil impurity
Sildenafil DiMer IMpurity
SILDENAFIL N-OXIDE
7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,6-dihydro-5-(2-hydroxyphenyl)-1-methyl-3-propyl-
4-ethoxy-3-(1-methyl-7-oxo-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-5-yl)benzenesulfonamide
1-Methyl-4-nitro-3-propyl-(1H)-pyrazole-5-carboxamide
5-[2-Ethoxy-5-[(4-Methyl-4-oxido-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-Methyl-3-(2-Methylpropyl)-7H-pyrazolo[4,3-d]pyriMidin-7-one
Desethyl Sildenafil
1-METHYL-4-NITRO-3-PROPYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
1H-PYRAZOLE-5-CARBOXAMIDE, 4-[[2-ETHOXY-5-[(4-METHYL-1-PIPERAZINYL)SULFONYL]BENZOYL]AMINO]-1-METHYL-3-PROPYL-
4-AMINO-1-METHYL-5-PROPYL-1H-PYRAZOLE-3-CARBOXYLIC ACID AMIDE
1of4
Thiosildenafil
Demethyltadalafil Solution, 100ppm
5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidine-7-thione
Sildenafil N
Sildenafil Impurity N
Sildenafil Impurity 23/Thiosildenafil/5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidine-7-thione
7H-Pyrazolo[4,3-d]pyrimidine-7-thione, 5-[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-
5-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidine-7(6H)-thione
xidi
ethyl4-amino-1-methyl-3-propyl-1H-pyrazole-5-carboxylate
Thiosildenafil in Methanol
Pinacolborane Impurity 5
479073-79-5
171596-83-6
C22H27D3N6O3S2
C22H30N6O3S2
Drug Analogues
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals
Sulfur & Selenium Compounds
Isotope Labelled Compounds
A
1