MOPS
- CAS No.
- 1132-61-2
- Chemical Name:
- MOPS
- Synonyms
- MOPS;3-(N-MORPHOLINO)PROPANESULFONIC ACID;MOPS FREE ACID;MORPHOLINOPROPANE SULFONIC ACID;3-Morpholinopropanesulfoinc Acid;4-morpholinopropanesulphonic acid;3-Morpholinopropane-1-sulfonic acid;WAS 15;MOPS,≥98%;MOPS1132-61-2
- CBNumber:
- CB0221586
- Molecular Formula:
- C7H15NO4S
- Molecular Weight:
- 209.26
- MDL Number:
- MFCD00006183
- MOL File:
- 1132-61-2.mol
- MSDS File:
- SDS
| Melting point | 277-282 °C |
|---|---|
| Density | 1.3168 (rough estimate) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.6370 (estimate) |
| Flash point | 116 °C |
| storage temp. | room temp |
| solubility | H2O: 1 M at 20 °C, clear |
| form | Powder/Solid |
| color | White |
| PH Range | 6.5 - 7.9 |
| Odor | Odorless |
| PH | 2.5-4.0 (25℃, 1M in H2O) |
| pka | 7.2(at 25℃) |
| Water Solubility | 1000 g/L (20 ºC) |
| λmax |
λ: 260 nm Amax: 0.020 λ: 280 nm Amax: 0.015 |
| Merck | 14,6265 |
| BRN | 1106776 |
| Stability | Stable. Incompatible with strong bases, strong oxidizing agents. |
| InChIKey | DVLFYONBTKHTER-UHFFFAOYSA-N |
| LogP | -2.94 at 20℃ |
| CAS DataBase Reference | 1132-61-2(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 273BP63NV3 |
| EPA Substance Registry System | 4-Morpholinepropanesulfonic acid (1132-61-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338-P280a-P304+P340-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | QE9104530 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29349990 | |||||||||
| NFPA 704 |
|
MOPS price More Price(119)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHG0007 | MOPS | 1132-61-2 | 1KIT | $1191 | 2024-03-01 | Buy |
| Sigma-Aldrich | M3183 | MOPS BioPerformance Certified, suitable for cell culture, ≥99.5% (titration) | 1132-61-2 | 25KG | $9130 | 2024-03-01 | Buy |
| Sigma-Aldrich | M1254 | MOPS ≥99.5% (titration) | 1132-61-2 | 25KG | $7580 | 2024-03-01 | Buy |
| Sigma-Aldrich | 69947 | MOPS BioUltra, for molecular biology, ≥99.5% (T) | 1132-61-2 | 25g | $133 | 2024-03-01 | Buy |
| Sigma-Aldrich | 69947 | MOPS BioUltra, for molecular biology, ≥99.5% (T) | 1132-61-2 | 100g | $414 | 2024-03-01 | Buy |
MOPS Chemical Properties,Uses,Production
Description
MOPS (3-morpholinopropanesulfonic acid) is a buffer introduced by Good et al. in the 1960s. It is a structural analog to MES. Its chemical structure contains a morpholine ring. HEPES is a similar pH buffering compound that contains a piperazine ring. With a pKa of 7.20, MOPS is an excellent buffer for many biological systems at near-neutral pH.It is used as a synthetic buffering agent below pH 7.5.
application
MOPS is frequently used as a buffering agent in biology and biochemistry. It has been tested and recommended for polyacrylamide gel electrophoresis. Usage above 20 mM in mammalian cell culture work is not recommended. MOPS buffer solutions become discolored (yellow) over time, but reportedly slight discoloration does not significantly affect the buffering characteristics.
Reference
P. H. Quail, D. Marme, E. Schäfer, Particle-bound phytochrome from maize and pumpkin, Nature New Biology, 1973, vol. 245, pp. 189-191
Chemical Properties
White/clear crystalline powder
Uses
MOPS acts as a multi-purpose buffering agent used in various biological research.
Uses
Due to its inert nature, 3-morpholinopropanesulfonic acid (MOPS) is widely used as a buffer in many biochemical studies. MOPS has been used as a cell culture additive component in lentiviral particle production, a buffering agent in microbial growth medium and nuclei extraction buffer, a component of Roswell Park Memorial Institute (RPMI) medium for diluting fungal inoculum, and a buffer in capillary-zone electrophoresis to test performance. It is also used for the dilution of proteins from algal samples.
Definition
ChEBI: 3-(N-morpholino)propanesulfonic acid is a Good's buffer substance, pKa = 7.2 at 20 ℃. It is a member of morpholines, a MOPS and an organosulfonic acid. It is a conjugate acid of a 3-(N-morpholino)propanesulfonate. It is a tautomer of a 3-(N-morpholiniumyl)propanesulfonate.
General Description
3-(N-Morpholino)propane sulfonic acid (MOPS) is an N-substituted amino sulfonic acid with a morpholinic ring. MOPS is capable of buffering within a pH range of 6.5-7.9. MOPS is widely used in biological and biochemical studies due to its inert properties. It does not interact with any metal ions in solutions and has significant metal-buffer stability especially with copper (Cu), nickel (Ni), manganese (Mn), zinc (Zn), cobalt (Co) ions. MOPS buffer maintains the pH of the mammalian cell culture medium. MOPS functions to maintain pH in denaturing gel electrophoresis of RNA. MOPS can modify lipid interactions and influence the thickness and barrier properties of membranes. MOPS interacts with bovine serum albumin and stabilizes the protein. Hydrogen peroxide oxidizes MOPS slowly to N-oxide form.
Flammability and Explosibility
Not classified
Synthesis
Morpholine and 1,3-Propanesultone are added to absolute ethanol for reaction. The crude product synthesized is purified to obtain 3-Morpholinopropanesulfonic acid.
MOPS Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Xindesheng Material Technology Co., Ltd. | +8618971041571 | vickyzhao@whdschem.com | China | 174 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9414 | 58 |
| Suzhou Genemill Biotechnology Co.,Ltd | +8615862502491 | aimeegao@genemill.com | China | 39 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12840 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5857 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5893 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18154 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | sales02@sdzhonghuimaterial.com | China | 983 | 58 |
Related articles
- MOPS: Versatile Applications and its Production Method
- MOPS is a buffering agent used in biotechnology, produced via synthesis from 1,3-bromo-chloropropane and morpholine, purified ....
- Sep 2，2024
View Lastest Price from MOPS manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-24 | MOPS
1132-61-2
|
US $100.00-75.00 / kg | 1kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
 |
2024-11-22 | 3-Morpholinopropanesulfonic acid
1132-61-2
|
US $0.00 / KG | 1KG | 99% | 3500kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-11-21 | 3-Morpholinopropanesulfonic acid
1132-61-2
|
US $5.00 / KG | 1KG | 99.5% | 200mt/year | Jinan Finer Chemical Co., Ltd |
-
- MOPS
1132-61-2
- US $100.00-75.00 / kg
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-
- 3-Morpholinopropanesulfonic acid
1132-61-2
- US $0.00 / KG
- 99%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 3-Morpholinopropanesulfonic acid
1132-61-2
- US $5.00 / KG
- 99.5%
- Jinan Finer Chemical Co., Ltd