ChemicalBook >> CAS DataBase List >>Chloromethyl isopropyl carbonate
Chloromethyl isopropyl carbonate
- CAS No.
- 35180-01-9
- Chemical Name:
- Chloromethyl isopropyl carbonate
- Synonyms
- CMIC;Chloromethy Isopropyl carbonate;ALSTint-A08;Chloromethyl isoprop;Tenofovir Impurity 56;Tenofovir CMIC Impurity;Tenofovir Impurity 41 CRS;Tenofovir intermediate(CMIC);L-Propylchloromethylcarbonate;Chloromethyl isopropyl carbote
- CBNumber:
- CB0223267
- Molecular Formula:
- C5H9ClO3
- Molecular Weight:
- 152.58
- MDL Number:
- MFCD07375443
- MOL File:
- 35180-01-9.mol
Last updated:2024-10-24 21:11:16
| Boiling point | 66 °C(Press: 16 Torr) |
|---|---|
| Density | 1.14 |
| refractive index | 1.4110-1.4150 |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform (Slightly), DMSO, Ethyl Acetate (Slightly) |
| form | clear liquid |
| color | Colorless to Almost colorless |
| Stability | Moisture sensitive |
| InChI | InChI=1S/C5H9ClO3/c1-4(2)9-5(7)8-3-6/h4H,3H2,1-2H3 |
| InChIKey | JHYNXXBAHWPABC-UHFFFAOYSA-N |
| SMILES | C(OC(C)C)(=O)OCCl |
| CAS DataBase Reference | 35180-01-9(CAS DataBase Reference) |
| FDA UNII | 6S8MF45ZHW |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H317-H411 | |||||||||
| Precautionary statements | P280 | |||||||||
| Safety Statements | 24/25 | |||||||||
| RIDADR | 2924 | |||||||||
| HazardClass | 3/8 | |||||||||
| PackingGroup | Ⅲ | |||||||||
| HS Code | 29189900 | |||||||||
| NFPA 704 |
|
Chloromethyl isopropyl carbonate price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 1115705 | Chloromethyl isopropyl carbonate United States Pharmacopeia (USP) Reference Standard | 35180-01-9 | 100MG | $1360 | 2024-03-01 | Buy |
| TCI Chemical | C2626 | Chloromethyl Isopropyl Carbonate >98.0%(GC) | 35180-01-9 | 25g | $57 | 2024-03-01 | Buy |
| TCI Chemical | C2626 | Chloromethyl Isopropyl Carbonate >98.0%(GC) | 35180-01-9 | 100g | $170 | 2024-03-01 | Buy |
| Usbiological | 268404 | Chloromethyl isopropyl carbonate | 35180-01-9 | 5g | $360 | 2021-12-16 | Buy |
| TRC | C369230 | Chloromethyl Isopropyl Carbonate | 35180-01-9 | 100g | $470 | 2021-12-16 | Buy |
Chloromethyl isopropyl carbonate Chemical Properties,Uses,Production
Chemical Properties
Clear Colourless Liquid
Uses
Chloromethyl Isopropyl Carbonate is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor used as an anti-HIV agent.
Synthesis
At 0-5°C, a photoinitiator is added, and dimethyl carbonate and chlorine are subjected to light reaction. The reaction is stopped, and the product is distilled and separated to obtain dimethyl monochlorocarbonate. At 70-100°C, a catalyst is added, and dimethyl monochlorocarbonate and isopropanol are added to a distillation tower capable of controlling the reflux ratio. Methanol is distilled and separated under normal pressure while reacting. After the reaction is completed, excess isopropanol is distilled off under reduced pressure, and finally chloromethyl isopropyl carbonate is distilled under reduced pressure.
Chloromethyl isopropyl carbonate Preparation Products And Raw materials
Global( 483)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Vcan Advanced Material Co., Ltd. | +86-17306299870 +86-18652789875 | vcanam@vcanam.com | China | 32 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 | 1057@dideu.com | China | 3958 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12836 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5893 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | sales03@chemcn.cn | China | 970 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
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| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21638 | 55 |
| Hangzhou FandaChem Co.,Ltd. | +8615858145714 | FandaChem@Gmail.com | China | 9220 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
View Lastest Price from Chloromethyl isopropyl carbonate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-06 | Chloromethyl isopropyl carbonate
35180-01-9
|
US $0.00 / KG | 1KG | ≥99% | 200mt/year | Jinan Finer Chemical Co., Ltd | |
 |
2024-11-05 | Chloromethyl isopropyl carbonate
35180-01-9
|
US $30.00 / kg | 1kg | 98 | 2000kg | hebei hongtan Biotechnology Co., Ltd | |
 |
2024-10-11 | Chloromethyl Isopropyl Carbonate
35180-01-9
|
US $5.00-2.00 / KG | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD |
-
- Chloromethyl isopropyl carbonate
35180-01-9
- US $0.00 / KG
- ≥99%
- Jinan Finer Chemical Co., Ltd
-
- Chloromethyl isopropyl carbonate
35180-01-9
- US $30.00 / kg
- 98
- hebei hongtan Biotechnology Co., Ltd
-
- Chloromethyl Isopropyl Carbonate
35180-01-9
- US $5.00-2.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
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Chloromethyl Isopropyl Carbonate >
Tenofovir CMIC Impurity
TIANFU-CHEM - Chloromethyl isopropyl carbonate
Chloromethyl isopropyl carbonate [Tenofovir Disoproxil Fumarate Impurity
CMIC
Chloromethy Isopropyl carbonate
Tenofovir disoproxil Impurity 96
Tenofovir Impurity 41 CRS
35180-01-9
5180-1-9
Miscellaneous Reagents
Pharmaceutical Intermediates
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