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ChemicalBook >> CAS DataBase List >>(-)-4,6'-Dimethoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester

(-)-4,6'-Dimethoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester

(-)-4,6'-Dimethoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester Structure
(-)-4,6'-Dimethoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester structure
CAS No.
1900-29-4
Chemical Name:
(-)-4,6'-Dimethoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester
Synonyms
Trypacidin;(-)-4,6-Dimethoxy-6-methyl-3,4-dioxospiro[benzofuran-2(3H),1-[2,5]cyclohexadiene]-2-carboxylic acid methyl ester;(-)-4,6'-Dimethoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester;Spiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid, 4,6'-dimethoxy-6-methyl-3,4'-dioxo-, methyl ester, (-)-
CBNumber:
CB02307501
Molecular Formula:
C18H16O7
Molecular Weight:
344.32
MDL Number:
MFCD01684067
MOL File:
1900-29-4.mol
Last updated:2024-10-23 13:36:13
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(-)-4,6'-Dimethoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester Properties

Melting point 228-231 °C(Solv: methanol (67-56-1))
Boiling point 582.2±50.0 °C(Predicted)
Density 1.37±0.1 g/cm3(Predicted)
storage temp. -20°C
form A solid
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
NFPA 704
0
2 0

(-)-4,6'-Dimethoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Adipogen Life Sciences BVT-0442-M001 Trypacidin ≥98%(HPLC) 1900-29-4 1mg $110 2021-12-16 Buy
Product number Packaging Price Buy
BVT-0442-M001 1mg $110 Buy

(-)-4,6'-Dimethoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester Chemical Properties,Uses,Production

Biological Activity

Trypacidin is a fungal metabolite originally isolated from A. fumigatus.1 It is active against B. subtilis and M. bovis (MICs = 12.5 and 1.25 μg/ml, respectively), as well as T. cruzi and T. gondii (MICs = 5-10 and 10-20 μg/ml, respectively).1,2 It reduces viability and induces lysis of A549 human lung cancer cells (IC50s = 7.4 μM for both).3 Trypacidin increases survival in a mouse model of T. gondii infection when administered in six doses of 12.5 mg/kg each.1

storage

+4°C

References

1.Balan, J., Ebringer, L., Nemec, P., et al.Antiprotozoal antibiotics. II. Isolation and characterization of trypacidin, a new antibiotic, active against Trypanosoma cruzi and Toxoplasma gondiiJ. Antibiot. (Tokyo)16157-160(1963) 2.Song, Z., Liu, Y., Gao, J., et al.Antitubercular metabolites from the marine-derived fungus strain Aspergillus fumigatus MF029Nat. Prod. Res.1-8(2019) 3.Gauthier, T., Wang, X., Dos Santos, J.S., et al.Trypacidin, a spore-borne toxin from Aspergillus fumigatus, is cytotoxic to lung cellsPLoS One7(2)e29906(2012)

(-)-4,6'-Dimethoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

(-)-4,6'-Dimethoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester Suppliers

Global( 13)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
BOC Sciences 		16314854226; +16314854226 inquiry@bocsci.com United States 19741 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9804 58
Lynnchem 86-(0)29-85992781 17792393971 info@lynnchem.com China 4587 58
Novachemistry 44-20819178-90 02081917890 info@novachemistry.com United Kingdom 4381 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369 3477467573@qq.com China 8617 58
ChemeGen 中国 18818260767 2625930290@qq.com China 6973 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24644 58
Shanghai Saikerui Biotechnology Co. , Ltd. 021-58000709 15900491054 info@scrbio.com China 9502 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 6830 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
BOC Sciences 		58
Shanghai EFE Biological Technology Co., Ltd. 58
Lynnchem 58
Novachemistry 58
Changzhou Furuisi Biotechnology Co., Ltd 58
ChemeGen 中国 58
TargetMol Chemicals Inc. 58
Shanghai Saikerui Biotechnology Co. , Ltd. 58
Nanjing Tengyi Biotechnology Co., Ltd 58

View Lastest Price from (-)-4,6'-Dimethoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Trypacidin pictures 2024-10-24 Trypacidin
1900-29-4
 US $393.00 / mg 10g TargetMol Chemicals Inc.
  • Trypacidin pictures
  • Trypacidin
    1900-29-4
  • US $393.00 / mg
  • TargetMol Chemicals Inc.
(-)-4,6'-Dimethoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester Trypacidin Spiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid, 4,6'-dimethoxy-6-methyl-3,4'-dioxo-, methyl ester, (-)- (-)-4,6-Dimethoxy-6-methyl-3,4-dioxospiro[benzofuran-2(3H),1-[2,5]cyclohexadiene]-2-carboxylic acid methyl ester 1900-29-4