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ChemicalBook >> CAS DataBase List >>Δ2,2'-Bi[1,3-diselenole]

Δ2,2'-Bi[1,3-diselenole]

Δ2,2'-Bi[1,3-diselenole] Structure
Δ2,2'-Bi[1,3-diselenole] structure
CAS No.
54489-01-9
Chemical Name:
Δ2,2'-Bi[1,3-diselenole]
Synonyms
TSF;NKSF;Edodekin-α;IL-12 from rat;IL-12 from mouse;Tetraselenofulvalene;Tetraselenafulvalene;Δ2,2'-Bi[1,3-diselenole];Δ2,2'-Bi(1,3-diselenole);CTL maturation factor (TCMF)
CBNumber:
CB02378453
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
54489-01-9.mol
Last updated:2025-01-27 09:38:02
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Δ2,2'-Bi[1,3-diselenole] Properties

storage temp. -20°C
form lyophilized
biological source rat
UNSPSC Code 12352202
NACRES NA.32

Δ2,2'-Bi[1,3-diselenole] price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SRP3204 IL-12 from mouse recombinant, expressed in CHO cells, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture 54489-01-9 10μG $362 2024-03-01 Buy
American Custom Chemicals Corporation PRO0004906 CTL MATURATION FACTOR (TCMF) 95.00% 54489-01-9 5MG $496.78 2021-12-16 Buy
Product number Packaging Price Buy
SRP3204 10μG $362 Buy
PRO0004906 5MG $496.78 Buy

Δ2,2'-Bi[1,3-diselenole] Chemical Properties,Uses,Production

Biological Activity

IL-12 is a potent regulator of cell mediated immune responses and it induces IFN-g production by NK and T cells. Recombinant murine IL-12 is a 75.0 kDa heterodimeric glycoprotein consisting of disulfide-linked 35 kDa (p35) and 40 kDa (p40) subunits (506 total amino acid residues).', 'IL12 (interleukin 12) is crucial for the maturation of naive T cells into IFNγ (interferon)–producing Th1 (T helper) cells. IL12 mutant mice show higher susceptibility to bacterial infections due to significant reduction in the production of IFNγ. This protein functions as an early pro-inflammatory cytokine during infections. IL12 has potent anti-tumor effects in preclinical studies, which however, have not been reproduced in clinical studies. Studies in mice show th at IL12 plays a crucial role in immune response against methicillin-resistant Staphylococcus aureus (MRSA)-mediated lung infection. Mice treated exogenously with IL12 prior to being subjected to MRSA infection show enhanced bacterial clearance and non-fatality.

Δ2,2'-Bi[1,3-diselenole] synthesis

75619-06-6
54489-01-9
Synthesis of Δ2,2'-Bi[1,3-diselenole] from 1,3-Diselenole, 2-methylene-

Δ2,2'-Bi[1,3-diselenole] Preparation Products And Raw materials

Raw materials

Preparation Products

Δ2,2'-Bi[1,3-diselenole] Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
Riedel-de Haen AG -- United States 6773 87
Supplier Advantage
Riedel-de Haen AG 87
2-(1,3-Diselenol-2-ylidene)-1,3-diselenole Tetraselenafulvalene Tetraselenofulvalene TSF Δ2,2'-Bi(1,3-diselenole) Δ2,2'-Bi[1,3-diselenole] CTL maturation factor (TCMF) Cytotoxic lymphocyte maturation factor (CLMF) NKSF IL-12 from mouse Edodekin-α IL-12 from rat 54489-01-9