2-Methylpyrazine
- CAS No.
- 109-08-0
- Chemical Name:
- 2-Methylpyrazine
- Synonyms
- Pyrazine, methyl-;METHYLPYRAZINE;3-Methylpyrazine;2-METHYL-1,4-DIAZINE;MPZ;FEMA 3309;FEMA 3616;Methylpiazine;methyl-pyrazin;FEMA NUMBER 3309
- CBNumber:
- CB0237950
- Molecular Formula:
- C5H6N2
- Molecular Weight:
- 94.11
- MDL Number:
- MFCD00006142
- MOL File:
- 109-08-0.mol
| Melting point | -29 °C (lit.) |
|---|---|
| Boiling point | 135 °C/761 mmHg (lit.) |
| Density | 1.03 g/mL at 25 °C (lit.) |
| FEMA | 3309 | 2-METHYLPYRAZINE |
| refractive index |
n |
| Flash point | 122 °F |
| storage temp. | 2-8°C |
| solubility | >20.87 mg/mL in EtOH with ultrasonic; >49.9 mg/mL in DMSO; |
| pka | 1.45(at 27℃) |
| form | Liquid |
| color | Clear colorless to slightly yellow |
| Odor | at 1.00 % in dipropylene glycol. nutty cocoa roasted chocolate peanut green |
| Odor Type | nutty |
| Water Solubility | Fully miscible in water. |
| JECFA Number | 761 |
| BRN | 105778 |
| InChIKey | CAWHJQAVHZEVTJ-UHFFFAOYSA-N |
| LogP | 0.18 |
| CAS DataBase Reference | 109-08-0(CAS DataBase Reference) |
| Substances Added to Food (formerly EAFUS) | 2-METHYLPYRAZINE |
| EWG's Food Scores | 1 |
| FDA UNII | RVC6500U9C |
| NIST Chemistry Reference | Pyrazine, methyl-(109-08-0) |
| EPA Substance Registry System | Pyrazine, methyl- (109-08-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H226-H302 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P301+P312 | |||||||||
| Hazard Codes | Xn,Xi,F | |||||||||
| Risk Statements | 10-22-36/37/38 | |||||||||
| Safety Statements | 26-36-16 | |||||||||
| RIDADR | UN 1993 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UQ3675000 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29339990 | |||||||||
| Toxicity | mouse,LD50,intraperitoneal,1820mg/kg (1820mg/kg),Toxicology and Applied Pharmacology. Vol. 17, Pg. 244, 1970. | |||||||||
| NFPA 704 |
|
2-Methylpyrazine price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W330906 | 2-Methylpyrazine ≥99%, FCC, FG | 109-08-0 | 100g | $87.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | W330906 | 2-Methylpyrazine ≥99%, FCC, FG | 109-08-0 | 1kg | $175 | 2024-03-01 | Buy |
| Sigma-Aldrich | W330906 | 2-Methylpyrazine ≥99%, FCC, FG | 109-08-0 | 5kg | $627 | 2024-03-01 | Buy |
| Sigma-Aldrich | M75608 | 2-Methylpyrazine ≥99% | 109-08-0 | 25g | $32.5 | 2024-03-01 | Buy |
| Sigma-Aldrich | M75608 | 2-Methylpyrazine ≥99% | 109-08-0 | 100g | $56.2 | 2024-03-01 | Buy |
2-Methylpyrazine Chemical Properties,Uses,Production
Description
2-Methylpyrazine has an odor threshold in water variously reported at 60,000 or 105,000 ppb. May be prepared from the corresponding carboxylic acid; by catalytic dehydrogenation of 2-methyl-piperazine; by condensation of methylglyoxal with ethylenediamine.
Chemical Properties
clear colorless to slightly yellow liquid
Chemical Properties
2-Methylpyrazine has a nutty, cocoa, green, roasted, chocolate, meaty odor.
Occurrence
Reported found in bakery products, roasted barley, cocoa products, coffee, dairy products, cooked meats, peanuts, filberts, pecans, popcorn, potato chips, rum and whiskey, soy product, roasted filberts, roasted almonds, guava, papaya, asparagus, kohlrabi, baked and fried potato, milk, boiled egg, smoked fish, beer, coffee, sesame seed, rice, sukiyaki, buckwheat, sweet corn, corn tortillas, malt, wort, wild rice, okra, crayfish, clam, squid and maté.
Uses
2-Methylpyrazine is used as flavoring agents in bread fresh bread, butter, chocolate, chocolate cocoa, coffee, meat roasted, nut almond.
Uses
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Preparation
From corresponding carboxylic acid; by catalytic dehydrogenation of 2-methyl-piperazine; by condensation of methylglyoxal with ethylenediamine
Definition
ChEBI: Methylpyrazine is a member of the class of pyrazines that is pyrazine in which one of the hydrogens is replaced by a methyl group. It is a flavouring agent found in coffee, peanuts and red peppers. It has a role as a flavouring agent, a plant metabolite and a Maillard reaction product.
Aroma threshold values
Detection: 60 ppb to 100 ppm
Taste threshold values
Taste characteristics at 75 ppm: nutty, brown, musty, roasted and astringent
General Description
2-Methylpyrazine is an alkyl-substituted pyrazine used as a key intermediate in the synthesis of pyrazineamide, an anti-tubercular drug.
Safety Profile
Moderately toxic by ingestion and intraperitoneal routes. Mutation data reported. Flammable liquid when exposed to heat, sparks, or flame. Can react with oxidizing materials. To fight fire, use water spray, foam, dry chemical, CO2. When heated to decomposition it emits highly toxic fumes of NOx.
Purification Methods
Purify it via the picrate and distil the free base. The picrate has m133-134o(from EtOH). [Wiggins & Wise J Chem Soc 4780 1956, Beilstein 23 III/IV 911, 23/5 V 386.]
2-Methylpyrazine Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12467 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5999 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | info@tnjchem.com | China | 2989 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2967 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8822 | 58 |
| Cangzhou Wanyou New Material Technology Co.,Ltd | 18631714998 | sales@czwytech.com | CHINA | 906 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
View Lastest Price from 2-Methylpyrazine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2024-02-24 | 2-Methylpyrazine
109-08-0
|
US $0.00-0.00 / kg | 25kg | 99% | 10 tons | Hebei Yanxi Chemical Co., Ltd. | |
 |
2023-08-31 | 2-Methylpyrazine
109-08-0
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-03-06 | 2-Methylpyrazine
109-08-0
|
US $10.70 / kg | 10kg | 99% | 10000kg | Hebei Guanlang Biotechnology Co,.LTD |
-
- 2-Methylpyrazine
109-08-0
- US $0.00-0.00 / kg
- 99%
- Hebei Yanxi Chemical Co., Ltd.
-
- 2-Methylpyrazine
109-08-0
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- 2-Methylpyrazine
109-08-0
- US $10.70 / kg
- 99%
- Hebei Guanlang Biotechnology Co,.LTD