Nα-L-Valyl-N1-[1-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl)ethyl]glycinamide

Nα-L-Valyl-N1-[1-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl)ethyl]glycinamide structure

CAS No.: 53098-67-2

Chemical Name:: Nα-L-Valyl-N1-[1-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl)ethyl]glycinamide

Synonyms: Amphibine I;Glycinamide, L-valyl-N-[1-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)ethyl]-;Nα-L-Valyl-N1-[1-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl)ethyl]glycinamide

CBNumber:: CB02425744

Molecular Formula:: C21H34N4O4

Molecular Weight:: 406.52

MDL Number:

MOL File:: 53098-67-2.mol

Last updated:2023-07-12 16:40:43

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Nα-L-Valyl-N1-[1-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl)ethyl]glycinamide Properties

Boiling point	628.0±55.0 °C(Predicted)
Density	1.120±0.06 g/cm3(Predicted)
pka	13.80±0.46(Predicted)

Nα-L-Valyl-N1-[1-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl)ethyl]glycinamide Chemical Properties,Uses,Production

Description

A further alkaloid in the series of peptide bases obtained from Zizyphus amphibia A. Cheval., this base is obtained as a pale yellow foam and has no definite melting point. It is laevorotatory having a specific rotation of [α]²⁰_D - 50° (c 0.6, C6H6 ). The ultraviolet spectrum in MeOH has a single absorption maximum at 282 nm.

References

Tschesche, Spilles, Eckhardt, Chern. Ber., 107, 1329 (1974)

Nα-L-Valyl-N1-[1-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl)ethyl]glycinamide Preparation Products And Raw materials

Raw materials

Preparation Products

Amphibine I Nα-L-Valyl-N1-[1-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl)ethyl]glycinamide Glycinamide, L-valyl-N-[1-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)ethyl]- 53098-67-2