Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol Structure
2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol structure
CAS No.
760990-08-7
Chemical Name:
2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
Synonyms
3-Fluoro-4-hydroxyphenylboronic acid,pinacol ester;3-Fluoro-4-hydroxybenzeneboronic acid pinacol ester, 96%;2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol;Phenol, 2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
CBNumber:
CB02459392
Molecular Formula:
C12H16BFO3
Molecular Weight:
238.06
MDL Number:
MFCD11504962
MOL File:
760990-08-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-11-04 16:51:54
Request For Quotation

2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol Properties

Melting point 99.3-100.2 °C
Boiling point 324.9±32.0 °C(Predicted)
Density 1.15±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka 8.39±0.35(Predicted)
Appearance White to off-white Solid
CAS DataBase Reference 760990-08-7
Comptox DTXSID DTXSID50468772

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H303-H320
Precautionary statements  P312-P264-P305+P351+P338-P337+P313
HS Code  2931900090

2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 277972 4-Fluoro-3-hydroxyphenylboronic acid pinacol ester Asreported 760990-08-7 500mg $233 2026-06-03 Buy
Usbiological 277972 4-Fluoro-3-hydroxyphenylboronic acid pinacol ester Asreported 760990-08-7 1g $343 2026-06-03 Buy
Apolloscientific PC412427 3-Fluoro-4-hydroxyphenylboronic acid, pinacol ester >98% 760990-08-7 1g $21 2026-06-04 Buy
Apolloscientific PC412427 3-Fluoro-4-hydroxyphenylboronic acid, pinacol ester >98% 760990-08-7 5g $98 2026-06-04 Buy
Apolloscientific PC412427 3-Fluoro-4-hydroxyphenylboronic acid, pinacol ester >98% 760990-08-7 25g $481 2026-06-04 Buy
Product number Packaging Price Buy
277972 500mg $233 Buy
277972 1g $343 Buy
PC412427 1g $21 Buy
PC412427 5g $98 Buy
PC412427 25g $481 Buy

2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol Chemical Properties, Uses, Production

Uses

3-Fluoro-4-hydroxyphenylboronic acid, pinacol ester

Synthesis

4-Bromo-2-fluorophenol

2105-94-4

Bis(pinacolato)diboron

73183-34-3

2-FLUORO-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL

760990-08-7

4-Bromo-2-fluorophenol (1.9 g, 9.9 mmol), bis(pinacolato)diboron (2.9 g, 11.4 mmol), potassium acetate (3.90 g, 39.7 mmol), and DPPF (0.27 g, 0.49 mmol) were used as raw materials and dissolved in 32 mL 1,4-dioxane. Nitrogen was passed into the solution for 5 min to deoxidize. Subsequently, PdCl2(dppf)-DCM (0.4 g, 0.49 mmol) was added and the reaction mixture was stirred under reflux conditions for 4 hours. Upon completion of the reaction, the reaction solution was filtered through diatomaceous earth and purified by column chromatography to afford the target product 3-fluoro-4-hydroxyphenylboronic acid pinacol ester (2.2 g, 93% yield).1H NMR (CDCl3) δ 7.49 (2H, m), 6.98 (1H, t), 5.31 (1H, brs), 1.33 (12H, s).

References

[1] Patent: EP3239143, 2017, A2. Location in patent: Paragraph 0417
[2] Patent: US2010/324068, 2010, A1. Location in patent: Page/Page column 30
[3] Patent: WO2014/209034, 2014, A1. Location in patent: Paragraph 432; 433; 434
[4] Patent: CN105384638, 2016, A. Location in patent: Paragraph 0678; 0679; 0680; 0681
[5] Journal of Medicinal Chemistry, 2016, vol. 59, # 23, p. 10479 - 10497

2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol Preparation Products And Raw materials

Raw materials

4-Bromo-2-fluorophenol Bis(pinacolato)diboron 1,1'-Bis(diphenylphosphino)ferrocene 1,4-Dioxane Potassium Acetate

Preparation Products

2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol Suppliers

Global Suppliers ( 71)
Supplier Tel Email Country ProdList Advantage
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44567 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Accela ChemBio Co.,Ltd. 4000665055 marketing@accelachem.com China 10969 64
China Langchem Inc. 0086-21-58956006 China 7798 57
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8662 57
Shanghai Jian Chao Chemical Technology Co., Ltd. 150-2103-5486 18017383231 983544897@qq.com China 9334 55
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56
AllyChem Co., Ltd. 0411-62313318 13889470786 info@allychem.com China 1021 65
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Supplier Advantage
Alfa Aesar 84
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Accela ChemBio Co.,Ltd. 64
China Langchem Inc. 57
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Shanghai Jian Chao Chemical Technology Co., Ltd. 55
9ding chemical ( Shanghai) Limited 56
AllyChem Co., Ltd. 65
Bide Pharmatech Ltd. 60

View Latest Price from 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Fluoro-4-hydroxybenzeneboronic acid pinacol ester pictures 2024-02-13 3-Fluoro-4-hydroxybenzeneboronic acid pinacol ester
760990-08-7
 $350.00 1g 97 50 Kg R&D Scientific Inc.
2-FLUORO-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL pictures 2020-02-04 2-FLUORO-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL
760990-08-7
 1KG 98%; 99% 1kg; 5kg Career Henan Chemical Co

760990-08-7 (2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol) Related Search:

2-Aminopyridine-4-boronic acid pinacol ester 2,4,6-TriMethoxyphenylboronic acid, pinacol ester 2-Aminopyridine-5-boronic acid, pinacol ester 4,4,5,5-tetramethyl-2-(4-nitronaphthalen-1-yl)-1,3,2-dioxaborolane 3-Methyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenol
4-(4,4,5,5-TetraMethyl-[1,3,2]dioxaborolan-2-yl)-2-trifluoroMethyl-phenol 2-Methyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenol 3-Chloro-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenol 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-1-amine 3-Chloro-4-hydroxyphenylboronic acid, pinacol ester
3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

1of3

3-Fluoro-4-hydroxyphenylboronic acid,pinacol ester 3-Fluoro-4-hydroxybenzeneboronic acid pinacol ester, 96% Phenol, 2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 760990-08-7