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rac erythro-9-(2-Hydroxy-3-nonyl)adenine, Hydrochloride

CAS No.
81408-49-3
Chemical Name:
rac erythro-9-(2-Hydroxy-3-nonyl)adenine, Hydrochloride
Synonyms
EHNA monohydrochloride;(2R,3S)-EHNA hydrochloride
CBNumber:
CB02509381
Molecular Formula:
C14H24ClN5O
Molecular Weight:
313.82626
MDL Number:
MFCD00151066
MOL File:
81408-49-3.mol
Last updated:2023-05-18 11:31:05

rac erythro-9-(2-Hydroxy-3-nonyl)adenine, Hydrochloride Properties

Melting point 163-170°C
storage temp. Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility Soluble in DMSO > 10 mM
form Powder
FDA UNII UGQ2ATP3NK

rac erythro-9-(2-Hydroxy-3-nonyl)adenine, Hydrochloride Chemical Properties,Uses,Production

Chemical Properties

White to Off-White Solid

Uses

A potent inhibitor of phosphodiesterase II (PDE II) (IC50=800nM). Does ot inhibit other PDE isozymes (IC50>100uM). Inhibits the retrograde transport motor, dynein. Also inhibits adenosine deaminase (Ki=4nM).

Definition

ChEBI: A hydrochloride salt obtained by reaction of (2R,3S)-EHNA with one equivalent of hydrochloric acid. Selective inhibitor of cGMP-stimulated phosphodiesterase (PDE2) (IC50 = 0.8 - 4 M). Also a potent inhibitor of adenosine deaminase.

rac erythro-9-(2-Hydroxy-3-nonyl)adenine, Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

rac erythro-9-(2-Hydroxy-3-nonyl)adenine, Hydrochloride Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
NewCan Biotech Limited
+86-0571-86912261 +8613735419629 sales@newcanbio.com China 9980 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15421 60
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1991 58
(2R,3S)-EHNA hydrochloride EHNA monohydrochloride 81408-49-3 Nucleotides Bases & Related Reagents Inhibitors