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ChemicalBook >> CAS DataBase List >>3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol

3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol

3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol Structure
3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol structure
CAS No.
164658-13-3
Chemical Name:
3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol
Synonyms
CS-506;CGP 60474;CGP-60474;CGP 60474;CGP60474, 10 mM in DMSO;3-[[4-[2-(3-chloroanilino)pyrimidin-4-yl]pyridin-2-yl]amino]propan-1-ol;3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol;3-((4-(2-((3-Chlorophenyl)amino)pyrimidin-4-yl)pyridin-2-yl)amino)propan-1-ol;1-Propanol, 3-[[4-[2-[(3-chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-
CBNumber:
CB02514596
Molecular Formula:
C18H18ClN5O
Molecular Weight:
355.82
MDL Number:
MFCD00938945
MOL File:
164658-13-3.mol
Last updated:2025-04-17 18:22:24
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3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol Properties

Melting point 144-147℃
Boiling point 630.6±65.0 °C(Predicted)
Density 1.356
storage temp. 2-8°C(protect from light)
solubility Soluble in DMSO
form Powder
pka 14.93±0.10(Predicted)
color Light yellow to yellow
FDA UNII 16IP6G5MLC

3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 5471 CGP60474 ≥98%(HPLC) 164658-13-3 10 $169 2021-12-16 Buy
Tocris 5471 CGP60474 ≥98%(HPLC) 164658-13-3 50 $711 2021-12-16 Buy
TRC C291780 CGP60474 164658-13-3 100mg $1000 2021-12-16 Buy
ApexBio Technology A3303 CGP60474 164658-13-3 50mg $1008 2021-12-16 Buy
ChemScene CS-0024 CGP60474 98.70% 164658-13-3 100mg $1020 2021-12-16 Buy
Product number Packaging Price Buy
5471 10 $169 Buy
5471 50 $711 Buy
C291780 100mg $1000 Buy
A3303 50mg $1008 Buy
CS-0024 100mg $1020 Buy

3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol Chemical Properties,Uses,Production

Uses

CGP 60474 is type of protein kinase C inhibitor (ckd1/cdk2) used in the treatment of different cancers

Definition

ChEBI: 3-[[4-[2-(3-chloroanilino)-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol is a substituted aniline.

in vivo

CGP-60474 (10?mg/kg; i.p.) inhibits the IL-6 level and increases the survival rate in the LPS endotoxemia model[2].

Animal Model:C57Bl/6 mice (LPS endotoxemia model)[2]
Dosage:10?mg/kg
Administration:I.p.
Result:Had a higher survival rate.

IC 50

CDK1-Cyclin B: 26 nM (IC50); CDK2/cyclinE: 3 nM (IC50); cdk2/cyclin A: 4 nM (IC50); CDK4/cyclin D: 216 nM (IC50); Cdk5/p25: 10 nM (IC50); CDK7/cyclin H: 200 nM (IC50); CDK9/cycT: 13 nM (IC50); PKC

storage

Store at -20°C

3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol Preparation Products And Raw materials

Raw materials

Preparation Products

3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol Suppliers

Global( 97)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49732 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29808 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32159 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Chembest Research Laboratories Limited +86-21-20908456 sales@BioChemBest.com China 6005 61
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 12952 65
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9891 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
TargetMol Chemicals Inc. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
Chembest Research Laboratories Limited 61
BOC Sciences 65
Shanghai T&W Pharmaceutical Co., Ltd. 58

View Lastest Price from 3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-[[4-[2-(3-chloroanilino)pyrimidin-4-yl]pyridin-2-yl]amino]propan-1-ol pictures 2020-01-13 3-[[4-[2-(3-chloroanilino)pyrimidin-4-yl]pyridin-2-yl]amino]propan-1-ol
164658-13-3
 US $1.00 / g 1g 95-99% 1ton Career Henan Chemical Co
3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol pictures 2020-01-13 3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol
164658-13-3
 US $1.00 / g 1g 99% 200kg Career Henan Chemical Co

164658-13-3(3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol)Related Search:

4,4'-DDT CHLOROPHENYLSILANE 97
CGP 60474 3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol CS-506 3-[[4-[2-(3-chloroanilino)pyrimidin-4-yl]pyridin-2-yl]amino]propan-1-ol CGP-60474;CGP 60474 1-Propanol, 3-[[4-[2-[(3-chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]- 3-((4-(2-((3-Chlorophenyl)amino)pyrimidin-4-yl)pyridin-2-yl)amino)propan-1-ol CGP60474, 10 mM in DMSO 164658-13-3