VU-29
- CAS No.
- 890764-36-0
- Chemical Name:
- VU-29
- Synonyms
- VU-29;VU-29/VU29;VU-29, 10 mM in DMSO;N-(1,3-Diphenyl-1H-pyrazol-5-yl)-4-nitrobenzamide;N-(1,3-Diphenyl-1H-pyrazolo-5-yl)-4-nitrobenzamide;BenzaMide, N-(1,3-diphenyl-1H-pyrazol-5-yl)-4-nitro-;mGluR,hippocampal,inhibit,rat,LTP,VU29,potentiator,VU-29,allosteric,Metabotropic glutamate receptors,Inhibitor,LTD
- CBNumber:
- CB02526230
- Molecular Formula:
- C22H16N4O3
- Molecular Weight:
- 384.39
- MDL Number:
- MFCD12546140
- MOL File:
- 890764-36-0.mol
- MSDS File:
- SDS
VU-29 price More Price(30)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Tocris | 4458 | VU29 ≥99%(HPLC) | 890764-36-0 | 10 | $199 | 2021-12-16 | Buy |
Tocris | 4458 | VU29 ≥99%(HPLC) | 890764-36-0 | 50 | $738 | 2021-12-16 | Buy |
Usbiological | 257073 | VU 29 | 890764-36-0 | 10mg | $466 | 2021-12-16 | Buy |
TRC | D678873 | DPAP | 890764-36-0 | 2.5mg | $110 | 2021-12-16 | Buy |
ChemScene | CS-0028668 | VU-29 98.04% | 890764-36-0 | 5mg | $100 | 2021-12-16 | Buy |
VU-29 Chemical Properties,Uses,Production
Uses
DPAP is a potent, postive allosteric, potentiator at mGluR-5.
in vivo
VU-29 (500 nM) potentiates DHPG induced increases in phosphoinositide (PI) hydrolysis in rat hippocampal slices. VU-29 potentiates threshold TBS-induced long term potentiation (LTP) in rat hippocampal CA1 region. VU-29 (1 μM) potentiates chemically induced mGluR-long term depression (LTD) in area CA1 of the rat hippocampus. VU-29 (1 μM) potentiates stimulus-induced NMDA receptor-independent LTD[1].
IC 50
rat mGluR5: 9 nM (EC50); rat mGluR1: 557 nM (EC50); rat mGluR2: 1.5 μM (EC50); hmGluR4: 154 nM (EC50); rat mGluR5: 224 nM (Ki)
VU-29 Preparation Products And Raw materials
Raw materials
Preparation Products
VU-29 Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 5221 | 58 |
EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71829 | 60 |
Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 6187 | 55 |
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