ChemicalBook >> CAS DataBase List >>3-BrB-PP1
3-BrB-PP1
- CAS No.
- 956025-99-3
- Chemical Name:
- 3-BrB-PP1
- Synonyms
- 3-BrB-PP1;4-AMino-1-tert-butyl-3-(3-broMobenzyl)pyrazolo[3,4-d]pyriMidine;3-(3-bromobenzyl)-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine;3-[(3-bromophenyl)methyl]-1-tert-butylpyrazolo[3,4-d]pyrimidin-4-amine;3-[(3-BroMophenyl)Methyl]-1-(1,1-diMethylethyl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine;1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-[(3-bromophenyl)methyl]-1-(1,1-dimethylethyl)-
- CBNumber:
- CB02621476
- Molecular Formula:
- C16H18BrN5
- Molecular Weight:
- 360.25
- MDL Number:
- MOL File:
- 956025-99-3.mol
Last updated:2023-07-14 17:31:39
3-BrB-PP1 price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | A602985 | 4-Amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine | 956025-99-3 | 10mg | $185 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 62852 | 4-Amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine | 956025-99-3 | 10mg | $650 | 2021-12-16 | Buy |
3-BrB-PP1 Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
4-Amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine is a small molecule Akt inhibitor. The kinase Akt is a key signaling node in regulating cellular growth and survival.
Definition
ChEBI: 3-BrB-PP1 is a member of the class of pyrazolopyrimidines that is pyrazolo[3,4-d]pyrimidin-4-amine bearing additional tert-butyl and 3-bromobenzyl substituents at positions 1 and 3 respectively. It is an ATP-competitive inhibitor of CDPK1 and AKT kinase. It has a role as an antiparasitic agent, an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a pyrazolopyrimidine, a member of bromobenzenes and an aromatic amine.
Synthesis of 3-BrB-PP1 from 5-Amino-1-tert-butyl-3-(3-bromobenzyl)-1H-pyrazole-4-carbonitrile and formamide
3-BrB-PP1 Preparation Products And Raw materials
Raw materials
Preparation Products
3-BrB-PP1 Suppliers
Global( 10)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 +86-13028896684; | sales@rrkchem.com | China | 56354 | 58 |
| Suzhou Chenrui Biotechnology Co. LTD | 17625585511 | 1580084073@qq.com | China | 580 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 13675144456 | sean.lv@synzest.com | China | 11442 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 62163 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 4738 | 58 |
3-[(3-BroMophenyl)Methyl]-1-(1,1-diMethylethyl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine
3-BrB-PP1
4-AMino-1-tert-butyl-3-(3-broMobenzyl)pyrazolo[3,4-d]pyriMidine
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-[(3-bromophenyl)methyl]-1-(1,1-dimethylethyl)-
3-[(3-bromophenyl)methyl]-1-tert-butylpyrazolo[3,4-d]pyrimidin-4-amine
3-(3-bromobenzyl)-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
956025-99-3
C16H18BrN5
Bases & Related Reagent
Heterocycles
Nucleotides
Protein Kinase Inhibitors and Activators