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TAK875

CAS No.
1374598-80-7
Chemical Name:
TAK875
Synonyms
CS-1926;TAK-875(b);TAK-875(0.5H2O);TAK875 hemihydrate;TAK-875 hymihydrate;(3S)-6-[[2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-2,3-dihydro-3-benzofuranacetic acid hydrate (2:1);[(3S)-6-({2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy]biphe-nyl-3-yl}meth-oxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid hemi-hydrate;TAK875 (3S)-6-[[2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-2,3-dihydro-3-benzofuranacetic acid
CBNumber:
CB02660082
Molecular Formula:
C58H66O15S2
Molecular Weight:
1067.26564
MDL Number:
MFCD18251445
MOL File:
1374598-80-7.mol
MSDS File:
SDS
Last updated:2023-05-21 10:59:17

TAK875 Properties

storage temp. Store at -20°C
solubility DMSO: 100 mg/mL (187.40 mM);Ethanol: Insoluble
Water Solubility Water: Insoluble
InChIKey OJXYMYYDAVXPIK-IWKNALKQSA-N
CAS DataBase Reference 1374598-80-7
FDA UNII 8LDT91CH8A

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

TAK875 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Crysdot CD31003704 Fasiglifamhemihydrate 95+% 1374598-80-7 100mg $600 2021-12-16 Buy
Crysdot CD31003704 Fasiglifamhemihydrate 95+% 1374598-80-7 250mg $930 2021-12-16 Buy
Product number Packaging Price Buy
CD31003704 100mg $600 Buy
CD31003704 250mg $930 Buy

TAK875 Chemical Properties,Uses,Production

Characteristics

More potent at activating hGPR40 than oleic acid

Biological Activity

TAK-875 is a selective GPR40 agonist with EC50 of 14 nM, 400-fold more potent than oleic acid.

target

< td style="border-bottom: 1px dotted #ccc;padding: 5px;"> 14 nM(EC50)
TargetValue
GPR40
(CHO cells expressing human GPR40)

TAK875 Preparation Products And Raw materials

Raw materials

Preparation Products

TAK875 Suppliers

Global( 37)Suppliers
Supplier Tel Email Country ProdList Advantage
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8474 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
WinWin Chemical CO., Limited
+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14278 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 24607 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418684 +8618949823763 sales@tnjchem.com China 25363 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131980 58
ROSEWA HOLDING GROUP CO.,LIMITED
+86-023-62871537 sales@rosewachem.com China 2844 58
Wuhan ariel chemical Co., LTD. 18986259541 18986259541 sales@3stc.com China 3970 58
[(3S)-6-({2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy]biphe-nyl-3-yl}meth-oxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid hemi-hydrate TAK875 (3S)-6-[[2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-2,3-dihydro-3-benzofuranacetic acid TAK-875(0.5H2O) (3S)-6-[[2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-2,3-dihydro-3-benzofuranacetic acid hydrate (2:1) TAK875 hemihydrate CS-1926 TAK-875 hymihydrate TAK-875(b) 1374598-80-7 2C29H32O7SH2O C29H32O7S12H2O API Inhibitors