ChemicalBook >> CAS DataBase List >>2,4-Dihydroxybenzamide

2,4-Dihydroxybenzamide

CAS No.
3147-45-3
Chemical Name:
2,4-Dihydroxybenzamide
Synonyms
β-Resorcylamide;B-RESORCYL AMIDE;p-hydroxysaliamide;P-Hydroxysalicylamide;2,4-dihydroxy-benzamid;4-HYDROXY SALICYLAMIDE;2,4-DIHYDROXYBENZAMIDE;β-Resorcylic acid amide;2,4-Dihydroxybenzamide>Benzamide, 2,4-dihydroxy-
CBNumber:
CB0267944
Molecular Formula:
C7H7NO3
Molecular Weight:
153.14
MDL Number:
MFCD00064913
MOL File:
3147-45-3.mol
MSDS File:
SDS
Last updated:2024-07-30 15:00:37

2,4-Dihydroxybenzamide Properties

Melting point 228 °C
Boiling point 455.8±15.0 °C(Predicted)
Density 1.458±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol
form powder to crystal
pka 8.15±0.10(Predicted)
color White to Light red to Green
InChI InChI=1S/C7H7NO3/c8-7(11)5-2-1-4(9)3-6(5)10/h1-3,9-10H,(H2,8,11)
InChIKey IIUJCQYKTGNRHH-UHFFFAOYSA-N
SMILES C(N)(=O)C1=CC=C(O)C=C1O
CAS DataBase Reference 3147-45-3(CAS DataBase Reference)
EPA Substance Registry System Benzamide, 2,4-dihydroxy- (3147-45-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
HS Code  2924.29.7790
NFPA 704
0
2 0

2,4-Dihydroxybenzamide price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D3460 2,4-Dihydroxybenzamide >98.0%(HPLC)(T) 3147-45-3 5g $30 2024-03-01 Buy
TCI Chemical D3460 2,4-Dihydroxybenzamide >98.0%(HPLC)(T) 3147-45-3 25g $79 2024-03-01 Buy
TRC D678945 2,4-Dihydroxybenzamide 3147-45-3 100mg $45 2021-12-16 Buy
American Custom Chemicals Corporation CHM0007919 2,4-DIHYDROXYBENZAMIDE 95.00% 3147-45-3 5G $816.19 2021-12-16 Buy
AK Scientific J93198 2,4-Dihydroxybenzamide 3147-45-3 5g $40 2021-12-16 Buy
Product number Packaging Price Buy
D3460 5g $30 Buy
D3460 25g $79 Buy
D678945 100mg $45 Buy
CHM0007919 5G $816.19 Buy
J93198 5g $40 Buy

2,4-Dihydroxybenzamide Chemical Properties,Uses,Production

Uses

2,4-Dihydroxybenzamide is a specific inhibitor of glutathione reductase.

Synthesis

General procedure for preparation of 2,4-dihydroxybenzamide. It was prepared by the addition of 1.69 g (0.10 mol) methyl 2,4-dihydroxybenzoate in 10 mL of ammonia (pro analysis, 25% in water). The reaction mixture was stirred for 24 hours at room temperature. The excess ammonia and methanol formed during the reaction were removed under reduced pressure. Upon addition of 10 mL of water, the product was extracted by ether. Ether extracts were collected and washed with water, and after separation, the ether layer was dried over anhydrous sodium sulfate and evaporated under reduced pressure to give 2,4-dihydroxy benzamide. Crude products were purified by column chromatography using ethyl acetate as a mobile phase[1].

References

[1] Milena Jadrijevi?-Mladar Takac, Drazen Viki? Topi?. “FT-IR and NMR spectroscopic studies of salicylic acid derivatives. II. Comparison of 2-hydroxy- and 2,4- and 2,5-dihydroxy derivatives.” Acta Pharmaceutica 54 3 (2004): 177–91.

51-01-4
3147-45-3
Synthesis of 2,4-Dihydroxybenzamide from 2,4-diacetyloxybenzoic acid
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View Lastest Price from 2,4-Dihydroxybenzamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4-Dihydroxybenzamide pictures 2023-08-26 2,4-Dihydroxybenzamide
3147-45-3
US $100.00 / KG 1KG 99% 5000KG Hebei Mojin Biotechnology Co., Ltd
2,4-Dihydroxybenzamide pictures 2023-03-13 2,4-Dihydroxybenzamide
3147-45-3
US $0.00-0.00 / kg 1kg 98%Min 1000kg LY Global chemicals co.,ltd .
2,4-Dihydroxybenzamide pictures 2022-09-07 2,4-Dihydroxybenzamide
3147-45-3
US $0.00-0.00 / KG 1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
B-RESORCYL AMIDE 2,4-DIHYDROXY BENZOYLAMINE 2,4-DIHYDROXYBENZAMIDE 4-HYDROXY SALICYLAMIDE 2,4-Dihydroxybenzamide(P-Hydroxysalicylamide) 2,4-dihydroxy-benzamid p-hydroxysaliamide P-Hydroxysalicylamide 4-HYDROXYSALICYLAMIDE / 2,4-DIHYDROXYBENZAMIDE 4-HYDROXY SALICYLAMIDE HPLC 98.5+% β-Resorcylamide β-Resorcylic acid amide 2,4-Dihydroxybenzamide ISO 9001:2015 REACH 2,4-Dihydroxybenzamide> Benzamide, 2,4-dihydroxy- 3147-45-3 2147-45-3 Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts