14(S)-Hydroxy Docosahexaenoic Acid
- CAS No.
- 119433-37-3
- Chemical Name:
- 14(S)-Hydroxy Docosahexaenoic Acid
- Synonyms
- 14(S)-HDHA;14(S)-HDoHE;14(S) HDHA,14(S)HDHA;ZNEBXONKCYFJAF-OUKOMXQNSA-N;14(S)-Hydroxy Docosahexaenoic Acid;14(S)-hydroxy-4(Z),7(Z),10(Z),12(E),16(Z),19(Z)-docosahexaenoic acid;4,7,10,12,16,19-Docosahexaenoic acid, 14-hydroxy-, (4Z,7Z,10Z,12E,14S,16Z,19Z)-
- CBNumber:
- CB02694827
- Molecular Formula:
- C22H32O3
- Molecular Weight:
- 344.49
- MDL Number:
- MOL File:
- 119433-37-3.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H350 | |||||||||
| Precautionary statements | P201-P202-P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P308+P313-P370+P378-P403+P235-P405-P501 | |||||||||
| NFPA 704 |
|
14(S)-Hydroxy Docosahexaenoic Acid price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 15253 | 14(S)-HDHA ≥98% | 119433-37-3 | 25μg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 15253 | 14(S)-HDHA ≥98% | 119433-37-3 | 50μg | $152 | 2024-03-01 | Buy |
| Cayman Chemical | 15253 | 14(S)-HDHA ≥98% | 119433-37-3 | 100μg | $286 | 2024-03-01 | Buy |
| Cayman Chemical | 29142 | 14(S)-HDHA MaxSpec® Standard | 119433-37-3 | 10μg | $127 | 2023-06-20 | Buy |
| TRC | H939590 | 14(S)-HydroxyDocosahexaenoicAcid | 119433-37-3 | 25μg | $45 | 2021-12-16 | Buy |
14(S)-Hydroxy Docosahexaenoic Acid Chemical Properties,Uses,Production
Description
14(S)-HDHA is an oxygenation product formed by 12-lipoxygenase (12-LO) or 15-LO processing of docosahexaenoic acid (DHA; ). It is a precursor to the pro-resolving mediator maresin 1 and has been found in peritoneal exudates isolated from a mouse model of zymosan-induced peritonitis.
Uses
Docosahexaenoic acid (DHA; ) is a nutritionally-derived ω-3 fatty acid that is abundant in the brain and the retina and is thought to be important in early development and for therapeutic approaches to inflammatory disorders and cancer. 14(S)-HDHA is an oxygenation product of DHA that serves as a precursor to maresin 1 , an anti-inflammatory, pro-resolving mediator that prevents polymorphonuclear neutrophil (PMN) infiltration and stimulates macrophage phagocytosis. At doses as low as 0.2 ng/mouse 14(S)-HDHA administration resulted in reduced infiltration of PMNs into sites of inflammation.[Cayman Chemical]
Uses
14(S)-Hydroxy Docosahexaenoic Acid is formed by human platelets. 14(S)-Hydroxy Docosahexaenoic Acid reacts with activated macrophages to form dihydroxy-containg products which posses potent antiinflammatory and proresolving activity.
Definition
ChEBI: (14S)-HDoHE is a 14-HDoHE in which the stereocentre at position 14 has S-configuration. It is a conjugate acid of a (14S)-HDoHE(1-). It is an enantiomer of a (14R)-HDoHE.
14(S)-Hydroxy Docosahexaenoic Acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alfa Chemistry | Info@alfa-chemistry.com | United States | 24072 | 58 | |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94658 | 76 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8072 | 58 |
| Yichang Zhongyitai Trading Co., Ltd. | 0717-6449896 13886658719 | root@zhongyitai.com | China | 1977 | 58 |
| Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9171 | 60 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 56077 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44843 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |